Description
Antibody Name: | CSNK1A1L/CSNK1A1 Antibody (PACO23264) |
Antibody SKU: | PACO23264 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:50-1:100, IF:1:100-1:500 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthesized peptide derived from internal of human CKI- alpha 1/L. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry analysis of paraffin-embedded human testis tissue, using CKI-alpha 1/L antibody. | |
Immunofluorescence analysis of A549 cells, using CKI- alpha 1/L antibody. |
Background: | Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling By similarity. |
Synonyms: | CK1; CK1-alpha2; CKI-alpha; CSNK1A1L; EC 2.7.11.1 |
UniProt Protein Function: | CK1A2: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily. |
UniProt Protein Details: | Protein type:Kinase, protein; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; Protein kinase, CK1; CK1 group; CK1 family Chromosomal Location of Human Ortholog: 13q13.3 Cellular Component: cytoplasm; nucleus; ribonucleoprotein complex Molecular Function:protein serine/threonine kinase activity; ATP binding Biological Process: regulation of cell shape; peptidyl-serine phosphorylation; Wnt receptor signaling pathway; cell morphogenesis; phagocytosis |
UniProt Code: | Q8N752 |
NCBI GenInfo Identifier: | 212286065 |
NCBI Gene ID: | 122011 |
NCBI Accession: | Q8N752.2 |
UniProt Secondary Accession: | Q8N752,Q5T2N2, |
UniProt Related Accession: | Q8N752 |
Molecular Weight: | 337 |
NCBI Full Name: | Casein kinase I isoform alpha-like |
NCBI Synonym Full Names: | casein kinase 1, alpha 1-like |
NCBI Official Symbol: | CSNK1A1L |
NCBI Official Synonym Symbols: | CK1 |
NCBI Protein Information: | casein kinase I isoform alpha-like; CKI-alpha-like; casein kinase I alpha S-like |
UniProt Protein Name: | Casein kinase I isoform alpha-like |
UniProt Synonym Protein Names: | CK1 |
Protein Family: | Casein kinase |
UniProt Gene Name: | CSNK1A1L |
UniProt Entry Name: | KC1AL_HUMAN |