Description
system_update_alt Datasheet
| Product Name: | CRABP2 Antibody |
| Product Sku: | CPAB0539 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human CRABP2 mAb is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CRABP2 amino acids 1-138 purified from Ecoli. |
| Clone: | PAT2E11AT. |
| Reactivity: | Other bodies |
| Applications: | Western Blot, ELISA |
| Purification Method: | CRABP2 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
| Isotype: | IgG2a |
| Background: | CRABP2 NCBI Accession No: NP_001869 regulates the access of retinoic acid to the nuclear retinoic acid receptors. CRABP2 is involved in a regulatory feedback mechanism that controls the action of retinoic acid on cell differentiation. CRABP2 is involved in the conversion of vitamin A into its intracellular active form retinoic acid, which regulate the genes responsible for lipid metabolism and adipocyte differentiation. CRABP2 gene is located on chromosome 1q21-23 and this region has been linked with related disorders such as familial combined hyperlipidemia (FCHL) and type 2 diabetes mellitus. CRABP proteins are of low molecular weight having an important function in retinoic acid-mediated regulation of human skin growth and differentiation. |
| Synonyms: | RBP6, CRABP-II, CRABP2, RETINOIC ACID-BINDING PROTEIN CELLULAR TYPE II, Cellular retinoic acid-binding protein 2, Cellular retinoic acid-binding protein II. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |