CRABP2 Monoclonal Antibody [PAT2E11AT] (CPAB0539)

Name: CRABP2 Monoclonal Antibody [PAT2E11AT] (CPAB0539)
SKU: CPAB0539
Availability: OutOfStock

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Signal Transduction Antibodies 3

system_update_alt Datasheet Overview

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Product Name:	CRABP2 Antibody
Product Sku:	CPAB0539
Size:	5μg
Host Species:	Mouse
Immunogen:	Anti-human CRABP2 mAb is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CRABP2 amino acids 1-138 purified from Ecoli.
Clone:	PAT2E11AT.
Reactivity:	Other bodies
Applications:	Western Blot, ELISA

Purification Method:	CRABP2 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:	IgG2a
Background:	CRABP2 NCBI Accession No: NP_001869 regulates the access of retinoic acid to the nuclear retinoic acid receptors. CRABP2 is involved in a regulatory feedback mechanism that controls the action of retinoic acid on cell differentiation. CRABP2 is involved in the conversion of vitamin A into its intracellular active form retinoic acid, which regulate the genes responsible for lipid metabolism and adipocyte differentiation. CRABP2 gene is located on chromosome 1q21-23 and this region has been linked with related disorders such as familial combined hyperlipidemia (FCHL) and type 2 diabetes mellitus. CRABP proteins are of low molecular weight having an important function in retinoic acid-mediated regulation of human skin growth and differentiation.
Synonyms:	RBP6, CRABP-II, CRABP2, RETINOIC ACID-BINDING PROTEIN CELLULAR TYPE II, Cellular retinoic acid-binding protein 2, Cellular retinoic acid-binding protein II.
Storage Buffer:	For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.