CLEC4E Monoclonal Antibody [PAT16E3AT] (CPAB0431)

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SKU:
CPAB0431
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT16E3AT
Applications:
WB
Applications:
IF
Applications:
ELISA

Description

system_update_alt Datasheet
Product Name:CLEC4E Antibody
Product Sku:CPAB0431
Size:5μg
Host Species:Mouse
Immunogen:Anti-human CLEC4E mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CLEC4E amino acids 41-219 purified from Ecoli.
Clone:PAT16E3AT.
Reactivity:Human
Applications:Western Blot, Immunofluorescence, ELISA
Purification Method:CLEC4E antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2b
Background:CLEC4E (MINCLE or CLECSF9), belongs to a diverse family of proteins which were originally defined by their ability to recognize a wide range of ligands of carbohydrate structure. MINCLE is expressed in macrophages subjected to several types of stress. CLEC4E has an important role in response to trehalose-6,6''-dimycolate (TDM) and activated by a synthetic analogue, trehalose dibehenate (TDB). It was reported recently that MINCLE is connected with an immunoreceptor tyrosine-based activation motif containing Fc receptor gamma chain (FcRgamma) and functions as an activating receptor for damaged self- and non-self-pathogenic fungi.
Synonyms:C-type lectin domain family 4 member E, C-type lectin superfamily member 9, Macrophage-inducible C-type lectin, CLEC4E, CLECSF9, MINCLE.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.
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