cGAS Polyclonal Antibody (CAB23846)
- SKU:
- CAB23846
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
Description
| Product Name: | cGAS Polyclonal Antibody |
| Product Code: | CAB23846 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:1000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Positive Samples: | C2C12 |
Enables several functions, including 2', 3'-cyclic GMP-AMP synthase activity; chromatin binding activity; and phosphatidylinositol-4, 5-bisphosphate binding activity. Involved in several processes, including cellular response to exogenous dsRNA; positive regulation of intracellular signal transduction; and regulation of defense response. Located in several cellular components, including cytosol; nucleus; and site of double-strand break.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 400-500 of human CGAS(NP_612450.2). |
| Sequence: | KEEKC CRKDC LKLMK YLLEQ LKERF KDKKH LDKFS SYHVK TAFFH VCTQN PQDSQ WDRKD LGLCF DNCVT YFLQC LRTEK LENYF IPEFN LFSSN LIDKR S |
| Synonyms: | MB21D1, h-cGAS, C6orf150 |
| Calculated MW: | 59kDa |
| Observed MW: | 62kDa |
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