CELSR3 Antibody (PACO23311)
- SKU:
- PACO23311
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CELSR3 Antibody (PACO23311) |
| Antibody SKU: | PACO23311 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:50-1:100, IF:1:100-1:500 |
| Species Reactivity: | Human |
| Immunogen: | Synthesized peptide derived from internal of human CELSR3. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry analysis of paraffin-embedded human brain tissue using CELSR3 antibody. |
 | Immunofluorescence analysis of HepG2 cells, using CELSR3 antibody. |
| Background: | Receptor that may have an important role in cell/cell signaling during nervous system formation. |
| Synonyms: | Cadherin EGF LAG seven-pass G-type receptor 3 ; Flamingo homolog 1; hFmi1; Multiple epidermal growth factor-like domains 2; Epidermal growth factor-like 1 |
| UniProt Protein Function: | CELSR3: Receptor that may have an important role in cell/cell signaling during nervous system formation. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 2 isoforms of the human protein are produced by alternative splicing.Protein type: GPCR, family 2; Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCRChromosomal Location of Human Ortholog: 3p21.31Cellular Component: plasma membrane; integral to membraneMolecular Function: G-protein coupled receptor activity; protein binding; calcium ion bindingBiological Process: G-protein coupled receptor protein signaling pathway; regulation of protein localization; neuron migration; axonal fasciculation; cilium biogenesis; homophilic cell adhesion |
| UniProt Protein Details: | |
| NCBI Summary: | This gene belongs to the flamingo subfamily, which is included in the cadherin superfamily. The flamingo cadherins consist of nonclassic-type cadherins that do not interact with catenins. They are plasma membrane proteins containing seven epidermal growth factor-like repeats, nine cadherin domains and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic feature of their subfamily. The encoded protein may be involved in the regulation of contact-dependent neurite growth and may play a role in tumor formation. [provided by RefSeq, Jun 2013] |
| UniProt Code: | Q9NYQ7 |
| NCBI GenInfo Identifier: | 145309304 |
| NCBI Gene ID: | 1951 |
| NCBI Accession: | NP_001398.2 |
| UniProt Secondary Accession: | Q9NYQ7,O75092 |
| UniProt Related Accession: | Q9NYQ7 |
| Molecular Weight: | Predicted Molecular Mass: 29.6kDaAccurate Molecular Mass: 29kDa as determined by SDS-PAGE reducing conditions. |
| NCBI Full Name: | cadherin EGF LAG seven-pass G-type receptor 3 |
| NCBI Synonym Full Names: | cadherin, EGF LAG seven-pass G-type receptor 3 |
| NCBI Official Symbol: | CELSR3 |
| NCBI Official Synonym Symbols: | FMI1; EGFL1; HFMI1; MEGF2; ADGRC3; CDHF11; RESDA1 |
| NCBI Protein Information: | cadherin EGF LAG seven-pass G-type receptor 3 |
| UniProt Protein Name: | Cadherin EGF LAG seven-pass G-type receptor 3 |
| UniProt Synonym Protein Names: | Cadherin family member 11; Epidermal growth factor-like protein 1; EGF-like protein 1; Flamingo homolog 1; hFmi1; Multiple epidermal growth factor-like domains protein 2; Multiple EGF-like domains protein 2 |
| Protein Family: | Cadherin EGF LAG seven-pass G-type receptor |
| UniProt Gene Name: | CELSR3 |
| UniProt Entry Name: | CELR3_HUMAN |
Related Products
SIM1 Antibody
Overview Product Name:SIM1 AntibodyProduct Code:PACO64949Size:50µLTarget Names:SIM1Species Reactivity:HumanHost
eutC Antibody
Overview Product Name:eutC AntibodyProduct Code:PACO64709Size:50µLTarget Names:eutCSpecies Reactivity:Escherichia coli
EPHA10 Antibody
Overview Product Name:EPHA10 AntibodyProduct Code:PACO64693Size:50µLTarget Names:EPHA10Species Reactivity:HumanH
otsB Antibody
Overview Product Name:otsB AntibodyProduct Code:PACO64885Size:50µLTarget Names:otsBSpecies Reactivity:Escherichia coli
PCDHA8 Antibody
Overview Product Name:PCDHA8 AntibodyProduct Code:PACO64893Size:50µLTarget Names:PCDHA8Species Reactivity:HumanH
SPEF2 Antibody
Overview Product Name:SPEF2 AntibodyProduct Code:PACO64977Size:50µLTarget Names:SPEF2Species Reactivity:HumanHos