CD8 Monoclonal Antibody [NYRmCD8] (CPAB0364)
![CD8 Monoclonal Antibody [NYRmCD8] (CPAB0364)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58586/63768/cd8-monoclonal-antibody-nyrmcd8-cpab0364__59277__96954.1706535150.jpg?c=1 "CD8 Monoclonal Antibody [NYRmCD8] (CPAB0364)")
- SKU:
- CPAB0364
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Rat
- Isotype:
- IgM
- Clone:
- NYRmCD8
![CD8 Monoclonal Antibody [NYRmCD8] (CPAB0364)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58586/63768/cd8-monoclonal-antibody-nyrmcd8-cpab0364__59277__96954.1706535150.jpg?c=1&imbypass=on "CD8 Monoclonal Antibody [NYRmCD8] (CPAB0364)")
Description
system_update_alt Datasheet
| Product Name: | CD8 Antibody |
| Product Sku: | CPAB0364 |
| Size: | 500μg |
| Host Species: | Rat |
| Immunogen: | Purified Mouse LN T cells. |
| Clone: | NYRmCD8. |
| Reactivity: | Mouse |
| Applications: |
| Purification Method: | Ion Exchange Column. |
| Isotype: | IgM |
| Background: | CD8 is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 acts as a co-receptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional CD8 is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8 identifies cytotoxic/suppressor t-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of t-cell mediated killing. CD8 alpha chains bind to class-I MHC molecules alpha-3 domains. |
| Synonyms: | CD8, MAL, p32. |
| Storage Buffer: | Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. |
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