CD74 Polyclonal Antibody (CAB24487)
- SKU:
- CAB24487
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | CD74 Polyclonal Antibody |
| Product Code: | CAB24487 |
| Reactivity: | Mouse |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Mouse |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | Mouse thymus |
Enables MHC class II protein binding activity; cytokine receptor activity; and nitric-oxide synthase binding activity. Contributes to cytokine binding activity. Involved in several processes, including macrophage migration inhibitory factor signaling pathway; positive regulation of macromolecule metabolic process; and regulation of signal transduction. Acts upstream of or within several processes, including antigen processing and presentation of exogenous peptide antigen via MHC class II; regulation of T cell differentiation; and thymic T cell selection. Located in several cellular components, including Golgi apparatus; external side of plasma membrane; and multivesicular body. Part of MHC class II protein complex; NOS2-CD74 complex; and macrophage migration inhibitory factor receptor complex. Is expressed in lower jaw; lower jaw incisor; lower jaw molar; and thymus primordium. Orthologous to human CD74 (CD74 molecule).
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 56-215 of mouse CD74 (NP_034675.1). |
| Sequence: | QQQGR LDKLT ITSQN LQLES LRMKL PKSAK PVSQM RMATP LLMRP MSMDN MLLGP VKNVT KYGNM TQDHV MHLLT RSGPL EYPQL KGTFP ENLKH LKNSM DGVNW KIFES WMKQW LLFEM SKNSL EEKKP TEAPP KEPLD MEDLS SGLGV TRQEL GQVTL |
| Synonyms: | Ii, CLIP, DHLAG, HLADG, Ia-GAMMA |
| Calculated MW: | 24kDa |
| Observed MW: | 34kDa |
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