CD73 Monoclonal Antibody [P2B6AT] (CPAB0338)
![CD73 Monoclonal Antibody [P2B6AT] (CPAB0338)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58560/63742/cd73-monoclonal-antibody-p2b6at-cpab0338__81811__91611.1706535142.jpg?c=1 "CD73 Monoclonal Antibody [P2B6AT] (CPAB0338)")
- SKU:
- CPAB0338
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG2b
- Clone:
- P2B6AT
- Applications:
- WB
- Applications:
- ELISA
![CD73 Monoclonal Antibody [P2B6AT] (CPAB0338)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58560/63742/cd73-monoclonal-antibody-p2b6at-cpab0338__81811__91611.1706535142.jpg?c=1&imbypass=on "CD73 Monoclonal Antibody [P2B6AT] (CPAB0338)")
Description
system_update_alt Datasheet
| Product Name: | CD73 Antibody |
| Product Sku: | CPAB0338 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human CD73 mAb , is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CD73 amino acids 27-252 purified from Ecoli. |
| Clone: | P2B6AT. |
| Reactivity: | Human |
| Applications: | Western Blot, ELISA |
| Purification Method: | CD73 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
| Isotype: | IgG2b |
| Background: | Ecto-5-prime-nucleotidase (5-prime-ribonucleotide phosphohydrolase) catalyzes the conversion of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP at a neutral pH. CD73, which consists of a dimer of 2 identical 70kDa subunits, is bound by a glycosyl phosphatidyl inositol linkage to the external face of the plasma membrane. CD73 is used as a marker of lymphocyte differentiation. Consequently, a deficiency of NT5 occurs in a variety of immunodeficiency diseases. Additional forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from ecto-NT5 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate. |
| Synonyms: | 5'-nucleotidase, Ecto-5'-nucleotidase, 5'-NT, CD73, NT5E, NT5, NTE, NT, eN, eNT, E5NT. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
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