CD3H Monoclonal Antibody
- SKU:
- CAB22473
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
Description
| Product Name: | CD3H Monoclonal Antibody |
| Product Code: | CAB22473 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC57083 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:1000-1:5000, IHC-P 1:200-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | MOLT-4, Mouse Thymus, Mouse spleen, Rat Thymus |
| Cellular Location: | Membrane |
The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 50-164 of human CD3H (NP_932170.1). |
| Sequence: | FLRVK FSRSA DAPAY QQGQN QLYNE LNLGR REEYD VLDKR RGRDP EMGGK PQRRK NPQEG LYNEL QKDKM AEAYS EIGMK GERRR GKGHD GLYQG LSTAT KDTYD ALHMQ ALPPR |
| Synonyms: | T3Z, CD3H, CD3Q, CD3Z, TCRZ, IMD25, CD3ZETA, CD3-ZETA |
| Calculated MW: | 19kDa |
| Observed MW: | 18kDa |
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