Description
Product Name: | CD36/SR-B3 Polyclonal Antibody |
Product Code: | CAB21716 |
Reactivity: | Mouse, Rat |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Mouse, Rat |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
Positive Samples: | Mouse heart, Rat heart |
Cellular Location: | Cell membrane, Multi-pass membrane protein |
The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 93-165 of CD36/SR-B3 (NP_000063.2). |
Sequence: | FEPSL SVGTE ADNFT VLNLA VAAAS HIYQN QFVQM ILNSL INKSK SSMFQ VRTLR ELLWG YRDPF LSLVP YPV |
Synonyms: | FAT, GP4, GP3B, GPIV, CHDS7, PASIV, SCARB3, BDPLT10 |
Calculated MW: | 53kDa |
Observed MW: | 70-110kDa |