CD319 monoclonal antibody (AGIM0216)

Name: CD319 monoclonal antibody (AGIM0216)
SKU: AGIM0216
Availability: OutOfStock

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Isotype:	IgG2b kappa
Host Species:	Mouse
Storage:	Store undiluted at 2-8°C.
Uniprot:	Q9NQ25
Background:	CD319 is a single-pass type l transmembrane glycoprotein, expressed on NK cells, subsets of mature dendritic cells, activated B cells, and cytotoxic lymphocytes, but not in promyelocytic, B or T cell lines. Expression is highest in the spleen, lymph nodes, and peripheral blood leukocytes, and lowest in bone marrow. Additionally, it is expressed in the small intestine, stomach, appendix, lung, and trachea. CD319 is tyrosine phosphorylated in activated NK cells and is associated with 19 and 39 kD proteins. CD319 has homology with the CD2 family of receptors within the Ig superfamily. Some of the CD2 members stimulate cytotoxicity through the CD319 associated protein.