CD30 Monoclonal Antibody
- SKU:
- CAB21230
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- IHC
- Applications:
- IF
- Applications:
- FC
Description
| Product Name: | CD30 Monoclonal Antibody |
| Product Code: | CAB21230 |
| Reactivity: | Human |
| Applications: | Immunohistochemistry, Immunofluorescence, Flow Cytometry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC52949 |
| Reactivity: | Human |
| Tested Applications: | IHC-P, IF/ICC, FC, ELISA |
| Key Applications: | Immunohistochemistry, Immunofluorescence, Flow Cytometry |
| Recommended Dilution: | IHC-P 1:100-1:500, IF/ICC 1:50-1:200, FC 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Cellular Location: | Cell membrane, Cytoplasm, Single-pass type I membrane protein |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 19-379 of human CD30 (NP_001234.3). |
| Sequence: | FPQDR PFEDT CHGNP SHYYD KAVRR CCYRC PMGLF PTQQC PQRPT DCRKQ CEPDY YLDEA DRCTA CVTCS RDDLV EKTPC AWNSS RVCEC RPGMF CSTSA VNSCA RCFFH SVCPA GMIVK FPGTA QKNTV CEPAS PGVSP ACASP ENCKE PSSGT IPQAK PTPVS PATSS ASTMP VRGGT RLAQE AASKL TRAPD SPSSV GRPSS DPGLS PTQPC PEGSG DCRKQ CEPDY YLDEA GRCTA CVSCS RDDLV EKTPC AWNSS RTCEC RPGMI CATSA TNSCA RCVPY PICAA ETVTK PQDMA EKDTT FEAPP LGTQP DCNPT PENGE APAST SPTQS LLVDS QASKT LPIPT SAPVA LSSTG K |
| Synonyms: | CD30, Ki-1, D1S166E |
| Calculated MW: | 14kDa/50kDa/63kDa |
| Observed MW: | Refer to figures |
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