CD163 Monoclonal Antibody
- SKU:
- CAB22619
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- IF
Description
| Product Name: | CD163 Monoclonal Antibody |
| Product Code: | CAB22619 |
| Reactivity: | Human |
| Applications: | Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC58325 |
| Reactivity: | Human |
| Tested Applications: | IF/ICC, ELISA |
| Key Applications: | Immunofluorescence |
| Recommended Dilution: | IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Cellular Location: | Cell membrane, Secreted |
| Customer Validation: | WB(Homo sapiens) IF(Homo sapiens) |
The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 861-961 of human CD163 (NP_004235.4). |
| Sequence: | GVVCR QLGCA DKGKI NPASL DKAMS IPMWV DNVQC PKGPD TLWQC PSSPW EKRLA SPSEE TWITC DNKIR LQEGP TSCSG RVEIW HGGSW GTVCD DSWDL D |
| Synonyms: | M130, MM130, SCARI1 |
| Calculated MW: | 125kDa |
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