CD14 PAT87H7AT Monoclonal Antibody [PAT87H7AT] (CPAB0343)

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SKU:
CPAB0343
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse

Description

system_update_alt Datasheet
Product Name:CD14 PAT87H7AT Antibody
Product Sku:CPAB0343
Size:5μg
Host Species:Mouse IgG2b
Immunogen:Anti-human CD14 mAb, clone PAT87H7AT, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CD14 protein 2-349 amino acids purified from Ecoli.
Clone:PAT87H7AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:CD14 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:
Background:CD14 (also known lipopolysaccharide (LPS) receptor) is expressed strongly on monocytes and macrophage and weakly on the surface of neutrophils. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14, also binding to LPS, acts at physiological concentration as an LPS agonist and has, at higher concentrations, an LPS antagonizing effect in cell activation. CD14 has been shown to bind apoptotic cells.
Synonyms:Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.
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