CD14 Monoclonal Antibody (CAB21256)
- SKU:
- CAB21256
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
Description
| Product Name: | CD14 Monoclonal Antibody |
| Product Code: | CAB21256 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC54507 |
| Reactivity: | Human |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | A-549, HepG2 |
| Cellular Location: | Cell membrane, GPI-anchor, Lipid-anchor, Secreted |
The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide, and to viruses. This gene has been identified as a target candidate in the treatment of SARS-CoV-2-infected patients to potentially lessen or inhibit a severe inflammatory response. Alternative splicing results in multiple transcript variants encoding the same protein.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-352 of human CD14 (NP_000582.1). |
| Sequence: | TTPEP CELDD EDFRC VCNFS EPQPD WSEAF QCVSA VEVEI HAGGL NLEPF LKRVD ADADP RQYAD TVKAL RVRRL TVGAA QVPAQ LLVGA LRVLA YSRLK ELTLE DLKIT GTMPP LPLEA TGLAL SSLRL RNVSW ATGRS WLAEL QQWLK PGLKV LSIAQ AHSPA FSCEQ VRAFP ALTSL DLSDN PGLGE RGLMA ALCPH KFPAI QNLAL RNTGM ETPTG VCAAL AAAGV QPHSL DLSHN SLRAT VNPSA PRCMW SSALN SLNLS FAGLE QVPKG LPAKL RVLDL SCNRL NRAPQ PDELP EVDNL TLDGN PFLVP GTALP HEGSM NSGVV PAC |
| Synonyms: | CD14 |
| Calculated MW: | 40kDa |
| Observed MW: | 50-60kDa |
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