Description
system_update_alt Datasheet
Product Name: | CD11a Antibody |
Product Sku: | CPAB0353 |
Size: | 500μg |
Host Species: | Rat |
Immunogen: | Enriched mouse peritoneal macrophages. |
Clone: | mCD11a. |
Reactivity: | Mouse |
Applications: |
Purification Method: | Ion exchange column. |
Isotype: | IgG2b |
Background: | ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. |
Synonyms: | Integrin, alpha L, CD11A, p180, alpha polypeptide, ITGAL, LFA-1, LFA1A TypeRat Anti Mouse Monoclonal. |
Storage Buffer: | Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. |