Description
system_update_alt Datasheet
Product Name: | CCR6 Antibody |
Product Sku: | CPAB0009 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human CCR6 mAb , is derived from hybridization of mouse Fmyeloma cells with spleen cells from BALB/c mice immunized with recombinant human CCR6 amino acids 1-46 purified from Ecoli. |
Clone: | P4C6AT. |
Reactivity: | Human |
Applications: | Western Blot, ELISA |
Purification Method: | CCR6 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
Isotype: | IgG1 |
Background: | CCR6 belongs to the beta chemokine receptor family, which is predicted to be a 7 transmembrane protein similar to G protein-coupled receptors. CCR6 is preferentially expressed by immature dendritic cells and memory T cells. The ligand of CCR6 receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). CCR6 receptor has been shown to be vital for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. |
Synonyms: | C-C chemokine receptor type 6, LARC receptor, GPR-CY4, Chemokine receptor-like 3, DRY6, G-protein coupled receptor 29, CD196, C-C CKR-6, CC-CKR-6, CCR-6, GPRCY4, CKR-L3, CCR6, CKRL3, CMKBR6, GPR29, STRL22, BN-1, CKR6, DCR2, DRY-6, GPRCY4, GPR-CY4. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |