Carboxypeptidase A1/CPA1 Recombinant Protein (RPES3995)

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SKU:
RPES3995
Product Type:
Recombinant Protein
Species:
Human

Description

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Carboxypeptidase A1/CPA1 Recombinant Protein

Carboxypeptidase A1 ?CPA1?is secreted as a pancreatic procarboxypeptidase, and cleaves the C-terminal amide or ester bond of peptides that have a free C-terminal carboxyl group, with the preference of  residues with aromatic or branched aliphatic side chains. CPA1 comprises a signal peptide, a pro region and a mature chain, and can be activated after cleavage of the pro peptide. In contrast to procarboxypeptidase B which was always secreted by the pancreas as a monomer, procarboxypeptidase A occurs as a monomer and/or associated to one or two functionally different proteins, such as zymogen E, and is involved in zymogen inhibition. Three different forms of human pancreatic procarboxypeptidase A have been isolated.

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