Calretinin Monoclonal Antibody (CAB21965)
- SKU:
- CAB21965
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
Description
| Product Name: | Calretinin Monoclonal Antibody |
| Product Code: | CAB21965 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC53565 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | WB 1:2000-1:10000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa, A-431, U-2 OS, Mouse brain, Rat brain |
| Cellular Location: | Cytosol, dendrite, Neuron projection, Nucleus, Parallel fiber to Purkinje cell synapse, Synapse, Terminal bouton |
This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Alternative splicing results in multiple transcript variants.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-271 of human Calretinin (NP_001731.2). |
| Sequence: | MAGPQ QQPPY LHLAE LTASQ FLEIW KHFDA DGNGY IEGKE LENFF QELEK ARKGS GMMSK SDNFG EKMKE FMQKY DKNSD GKIEM AELAQ ILPTE ENFLL CFRQH VGSSA EFMEA WRKYD TDRSG YIEAN ELKGF LSDLL KKANR PYDEP KLQEY TQTIL RMFDL NGDGK LGLSE MSRLL PVQEN FLLKF QGMKL TSEEF NAIFT FYDKD RSGYI DEHEL DALLK DLYEK NKKEM NIQQL TNYRK SVMSL AEAGK LYRKD LEIVL CSEPP M |
| Synonyms: | CR, CAL2, CAB29 |
| Calculated MW: | 32kDa |
| Observed MW: | 29kDa |
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