CALCR Polyclonal Antibody
- SKU:
- CAB10674
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | CALCR Polyclonal Antibody |
| Product Code: | CAB10674 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Positive Samples: | T-47D, MCF7 |
| Cellular Location: | Cell membrane, Multi-pass membrane protein |
This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-148 of human CALCR (NP_001733.1). |
| Sequence: | AFSNQ TYPTI EPKPF LYVVG RKKMM DAQYK CYDRM QQLPA YQGEG PYCNR TWDGW LCWDD TPAGV LSYQF CPDYF PDFDP SEKVT KYCDE KGVWF KHPEN NRTWS NYTMC NAFTP EKLKN AYVL |
| Synonyms: | CRT, CTR, CT-R, CTR1 |
| Calculated MW: | 55kDa |
| Observed MW: | 70kDa |
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