Description
system_update_alt Datasheet
Product Name: | BUB3 Antibody |
Product Sku: | CPAB0617 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human BUB3 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human BUB3 protein 1-328 amino acids purified from Ecoli. |
Clone: | PAT2H6AT. |
Reactivity: | Other bodies |
Applications: | Western Blot, ELISA |
Purification Method: | BUB3 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
Isotype: | IgG2b |
Background: | Mitotic checkpoint protein BUB3 (BUB3), is a saved component of the mitotic spindle assembly complex (MCC). The encoded protein has 4 WD repeat domains and has a similar sequence as the yeast BUB3 protein. BUB3 is vital for the kinetochore localization of BUB1 and BUBR1. BUB3 participates in the central spindle checkpoint pathway that operates during early embryogenesis. Furthermore BUB3 has a part in regulating the establishment of correct kinetochore-microtubule attachments. |
Synonyms: | BUB3L, hBUB3, Mitotic checkpoint protein BUB3. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |