Description
Product Name: | BOK Monoclonal Antibody |
Product Code: | CAB21196 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC53171 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:1000-1:5000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | PC-3, Mouse brain, Rat testis |
Cellular Location: | Endoplasmic reticulum membrane, Golgi apparatus membrane, Single-pass membrane protein |
The protein encoded by this gene belongs to the BCL2 family, members of which form homo- or heterodimers, and act as anti- or proapoptotic regulators that are involved in a wide variety of cellular processes. Studies in rat show that this protein has restricted expression in reproductive tissues, interacts strongly with some antiapoptotic BCL2 proteins, not at all with proapoptotic BCL2 proteins, and induces apoptosis in transfected cells. Thus, this protein represents a proapoptotic member of the BCL2 family.
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human BOK (NP_115904.1). |
Sequence: | MEVLR RSSVF AAEIM DAFDR SPTDK ELVAQ AKALG REYVH ARLLR AGLSW SAPER AAPVP GRLAE VCAVL LRLGD ELEMI RPSVY RNVAR QLHIS LQSEP |
Synonyms: | BOKL, BCL2L9 |
Calculated MW: | 23kDa |
Observed MW: | 23kDa |