Biotin Anti-Mouse CD51 Antibody [RMV-7]
- SKU:
- AGEL3347
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Applications:
- FCM
- Reactivity:
- Mouse
- Host Species:
- Rat
- Isotype:
- Rat IgG1, k
- Clone:
- RMV-7
- Conjugation:
- Biotin
Description
| Product Name: | Biotin Anti-Mouse CD51 Antibody [RMV-7] |
| Product Code: | AGEL3347 |
| Size: | 25ug, 100ug |
| Clone No: | RMV-7 |
| Synonyms: | Integrin alpha-V, αV integrin, Vitronectin Receptor, Integrin αV chain, ITGAV |
| Reactivity: | Mouse |
| Host Species: | Rat |
| Applications: | FCM |
| Isotype: | Rat IgG1, κ |
| Isotype Control: | Biotin Rat IgG1, κ Isotype Control [HRPN] |
| Conjugation: | Biotin |
| Applications: | FCM |
| Recommended Dilution: | Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
| Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Storage: | Keep as concentrated solution. Store at 2-8°C. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
| Shipping: | Biological ice pack at 4°C |
| Form: | Liquid |
| Gene ID: | 16410 |
| Swissprot: | P43406 |
| Background Information: | CD51 is a 140 kD protein, also known as αV integrin, vitronectin receptor, and integrin αV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins β1, β3, β5 or β6; these complexes then act as receptors for multiple extracellular matrix proteins (ECM). The αvintegrin heterodimers have varied functions in development, stimulation/activation and homeostasis. The primary ligands for CD51 complexes are fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, and CD31. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity. |
Related Products
APC Anti-Mouse CD51 Antibody [RMV-7] (AGEL2725)
OverviewProduct Name:APC Anti-Mouse CD51 Antibody [RMV-7] (AGEL2725)Product Code:AGEL2725Clone No:RMV-7Synonyms:Integrin alpha-V,
APC Anti-Mouse CD51 Antibody [RMV-7] (AGEL2726)
OverviewProduct Name:APC Anti-Mouse CD51 Antibody [RMV-7] (AGEL2726)Product Code:AGEL2726Clone No:RMV-7Synonyms:Integrin alpha-V,
PE Anti-Mouse CD51 Antibody [RMV-7] (AGEL2764)
OverviewProduct Name:PE Anti-Mouse CD51 Antibody [RMV-7] (AGEL2764)Product Code:AGEL2764Clone No:RMV-7Synonyms:Integrin alpha-V,α
PE Anti-Mouse CD51 Antibody [RMV-7] (AGEL2762)
OverviewProduct Name:PE Anti-Mouse CD51 Antibody [RMV-7] (AGEL2762)Product Code:AGEL2762Clone No:RMV-7Synonyms:Integrin alpha-V,α
PE/Cyanine7 Anti-Mouse CD51 Antibody [RMV-7] (AGEL2765)
OverviewProduct Name:PE/Cyanine7 Anti-Mouse CD51 Antibody [RMV-7] (AGEL2765)Product Code:AGEL2765Clone No:RMV-7Synonyms:Integrin