ATP6V1F Antibody (PACO28546)
- SKU:
- PACO28546
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ATP6V1F Antibody (PACO28546) |
| Antibody SKU: | PACO28546 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human V-type proton ATPase subunit F protein (1-119AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO28546 at dilution of 1:100. |
 | Immunofluorescent analysis of MCF-7 cells using PACO28546 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acid, fying a variety of intracellular compartments in eukaryotic cells. |
| Synonyms: | V-type proton ATPase subunit F (V-ATPase subunit F) (V-ATPase 14 kDa subunit) (Vacuolar proton pump subunit F), ATP6V1F, ATP6S14 VATF |
| UniProt Protein Function: | ATP6V1F: Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. Belongs to the V-ATPase F subunit family.Protein type: HydrolaseChromosomal Location of Human Ortholog: 7q32Cellular Component: cytosol; membrane; vacuolar proton-transporting V-type ATPase complexMolecular Function: ATPase activity, coupled to transmembrane movement of ions; protein bindingBiological Process: insulin receptor signaling pathway; transferrin transport |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is the V1 domain F subunit protein. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q16864 |
| NCBI GenInfo Identifier: | 126302612 |
| NCBI Gene ID: | 9296 |
| NCBI Accession: | Q16864.2 |
| UniProt Secondary Accession: | Q16864,Q6IBA8, C9J2K4 |
| UniProt Related Accession: | Q16864 |
| Molecular Weight: | 16,402 Da |
| NCBI Full Name: | V-type proton ATPase subunit F |
| NCBI Synonym Full Names: | ATPase H+ transporting V1 subunit F |
| NCBI Official Symbol: | ATP6V1F |
| NCBI Official Synonym Symbols: | VATF; Vma7; ATP6S14 |
| NCBI Protein Information: | V-type proton ATPase subunit F |
| UniProt Protein Name: | V-type proton ATPase subunit F |
| UniProt Synonym Protein Names: | V-ATPase 14 kDa subunit; Vacuolar proton pump subunit F |
| Protein Family: | |
| UniProt Gene Name: | ATP6V1F |
| UniProt Entry Name: | VATF_HUMAN |
| Antibodies |
| ATP6V1F Antibody (PACO07941) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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