ARMC10 Polyclonal Antibody
- SKU:
- CAB21304
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | ARMC10 Polyclonal Antibody |
| Product Code: | CAB21304 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | HepG2, MCF7 |
| Cellular Location: | Cytoplasm |
This gene encodes a protein that contains an armadillo repeat and transmembrane domain. The encoded protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 169-308 of human ARMC10 (NP_001154481.1). |
| Sequence: | TNMTV TNDHQ HMLHS YITDL FQVLL TGNGN TKVQV LKLLL NLSEN PAMTE GLLRA QVDSS FLSLY DSHVA KEILL RVLTL FQNIK NCLKI EGHLA VQPTF TEGSL FFLLH GEECA QKIRA LVDHH DAEVK EKVVT IIPKI |
| Synonyms: | SVH, PNAS112, PNAS-112, PSEC0198 |
| Calculated MW: | 38kDa |
| Observed MW: | 31-37kd |
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