Description
| Product Name: | Argonaute-2 Polyclonal Antibody |
| Product Code: | CAB24660 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:1000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | MCF7, HeLa, C6 |
| Cellular Location: | Cytoplasm, Nucleus, P-body |
This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing. Multiple transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 60-160 of human Argonaute-2 (NP_036286.2). |
| Sequence: | DIKPE KCPRR VNREI VEHMV QHFKT QIFGD RKPVF DGRKN LYTAM PLPIG RDKVE LEVTL PGEGK DRIFK VSIKW VSCVS LQALH DALSG RLPSV PFETI Q |
| Synonyms: | PPD, Q10, CASC7, EIF2C2, LESKRES, LINC00980 |
| Calculated MW: | 97kDa |
| Observed MW: | 95kDa |