APP Monoclonal Antibody [PJ4H9AT] (CPAB0555)
![APP Monoclonal Antibody [PJ4H9AT] (CPAB0555)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58776/63958/app-monoclonal-antibody-pj4h9at-cpab0555__97722__71510.1706535213.jpg?c=1 "APP Monoclonal Antibody [PJ4H9AT] (CPAB0555)")
- SKU:
- CPAB0555
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
- Isotype:
- IgG2b
- Clone:
- PJ4H9AT
- Applications:
- WB
- Applications:
- ELISA
![APP Monoclonal Antibody [PJ4H9AT] (CPAB0555)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58776/63958/app-monoclonal-antibody-pj4h9at-cpab0555__97722__71510.1706535213.jpg?c=1&imbypass=on "APP Monoclonal Antibody [PJ4H9AT] (CPAB0555)")
Description
system_update_alt Datasheet
| Product Name: | APP Antibody |
| Product Sku: | CPAB0555 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human APP mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human APP amino acids 18-289 purified from Ecoli. |
| Clone: | PJ4H9AT. |
| Reactivity: | Other bodies |
| Applications: | Western Blot, ELISA |
| Purification Method: | APP antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
| Isotype: | IgG2b |
| Background: | APP is a cell surface receptor and transmembrane precursor protein which is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in the APP gene are implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). |
| Synonyms: | Amyloid beta A4 protein, Alzheimer disease amyloid protein, ABPP, APPI, APP, PreA4, Cerebral vascular amyloid peptide, CVAP, Protease nexin-II, PN-II, A4, AD1, AAA, PN2, ABETA, CTFgamma. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
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