Metabolism Recombinant Proteins
Apolipoprotein A-I/ApoAI Recombinant Protein (RPES2825)
- SKU:
- RPES2825
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Metabolism
Description
Apolipoprotein A-I/ApoAI Recombinant Protein
The Apolipoprotein A1 (APOA1) protein is a secreted member of the Apolipoprotein A1/A4/E family. The major protein component of high-density lipoprotein (HDL) in plasma is APOA1. ApoA1 is a protein that has been linked to several physiological functions, such as cholesterol synthesis and metabolism; lipid synthesis and transport; and steroid synthesis. APOA1 promotes cholesterol efflux from tissues to the liver. Mutations in this gene cause HDL deficiencies, such as Tangier disease (TGD), systemic non-neuropathic amyloidosis, premature coronary artery disease, hepatosplenomegaly and progressive muscle wasting and weakness. ApoA-I is involved in the anti-endotoxin function of HDL via interaction with lipopolysaccharide or endotoxin. Apolipoprotein A-I/ApoAI Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
| Product Name: | Apolipoprotein A-I/ApoAI Recombinant Protein (RPES2825) |
| Product Code: | RPES2825 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Apolipoprotein A-I, Apo-AI, ApoA-I, Apolipoprotein A1, APOA1 |
| Accession: | P02647 |
| Sequence: | Arg19-Gln267 |
| Fusion tag: | |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Apolipoprotein A-I is produced by our E.coli expression system and the target gene encoding Arg19-Gln267 is expressed. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 29.0 kDa |
| AP Mol Mass: | 27-29 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB; 150mM NaCl; pH 7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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