Signal Transduction Antibodies 1

Anti-WSB1 Antibody (CAB12195)

(No reviews yet) Write a Review
SKU:
CAB12195
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-WSB1 Antibody
Antibody SKU:CAB12195
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 182-421 of human WSB1 (NP_056441.6).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:HT-29, A-549, HeLa, HepG2, SGC-7901
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 182-421 of human WSB1 (NP_056441.6).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:GSLI LVSA SRDK TLRV WDLK DDGN MMKV LRGH QNWV YSCA FSPD SSML CSVG ASKA VFLW NMDK YTMI RKLE GHHH DVVA CDFS PDGA LLAT ASYD TRVY IWDP HNGD ILME FGHL FPPP TPIF AGGA NDRW VRSV SFSH DGLH VASL ADDK MVRF WRID EDYP VQVA PLSN GLCC AFST DGSV LAAG THDG SVYF WATP RQVP SLQH LCRM SIRR VMPT QEVQ ELPI PSKL LEFL SYRI
Gene ID:26118
Uniprot:Q9Y6I7
Cellular Location:
Calculated MW:24kDa/27kDa/30kDa/47kDa
Observed MW:47kDa
Synonyms:WSB1, SWIP1, WSB-1
Background:This gene encodes a member of the WD-protein subfamily. This protein shares a high sequence identity to mouse and chick proteins. It contains several WD-repeats spanning most of the protein and an SOCS box in the C-terminus. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
UniProt Protein Function:Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes type II iodothyronine deiodinase/DIO2. Confers constitutive instability to HIPK2 through proteasomal degradation.
NCBI Summary:This gene encodes a member of the WD-protein subfamily. This protein shares a high sequence identity to mouse and chick proteins. It contains several WD-repeats spanning most of the protein and an SOCS box in the C-terminus. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Code:Q9Y6I7
NCBI GenInfo Identifier:20532298
NCBI Gene ID:26118
NCBI Accession:Q9Y6I7.1
UniProt Secondary Accession:Q9Y6I7,Q9NRB1, Q9UBH9, Q9UG25, Q9UNN6, Q9Y656,
UniProt Related Accession:Q9Y6I7
Molecular Weight:47kDa
NCBI Full Name:WD repeat and SOCS box-containing protein 1
NCBI Synonym Full Names:WD repeat and SOCS box containing 1
NCBI Official Symbol:WSB1  
NCBI Official Synonym Symbols:SWIP1; WSB-1  
NCBI Protein Information:WD repeat and SOCS box-containing protein 1
UniProt Protein Name:WD repeat and SOCS box-containing protein 1
UniProt Synonym Protein Names:SOCS box-containing WD protein SWiP-1
Protein Family:WD repeat and SOCS box-containing protein
UniProt Gene Name:WSB1  
Anti-WSB1 Antibody (CAB12195)Western blot analysis of extracts of various cell lines, using WSB1 antibody (CAB12195) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 10s.
View AllClose

0 Reviews

View AllClose

Related Products