Epigenetics & Nuclear Signaling Antibodies 5
Anti-WDR5 Antibody (CAB3259)
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- SKU:
- CAB3259
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Description
| Antibody Name: | Anti-WDR5 Antibody |
| Antibody SKU: | CAB3259 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human WDR5 |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Rat |
| Positive Samples: | HeLa, A-549, HT-1080, Rat testis |
| Immunogen: | A synthesized peptide derived from human WDR5 |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 11091 |
| Uniprot: | P61964 |
| Cellular Location: | |
| Calculated MW: | 36kDa |
| Observed MW: | 37KDa |
| Synonyms: | BIG-3, CFAP89, SWD3 |
| Background: | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008] |
| UniProt Protein Function: | WDR5: a WD40 repeat protein. May accelerate osteoblast differentiation. Interacts with HCFC1. WD40 repeats are found in a number of eukaryotic proteins that coordinate multi-protein complex assemblies. WD40 proteins are implicated in many functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. |
| UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 9q34 Cellular Component: histone acetyltransferase complex; histone methyltransferase complex; nucleoplasm; nucleus Molecular Function:histone acetyltransferase activity (H4-K16 specific); histone lysine N-methyltransferase activity (H3-K4 specific); histone-lysine N-methyltransferase activity; methylated histone residue binding; protein binding Biological Process: histone H3-K4 methylation |
| NCBI Summary: | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P61964 |
| NCBI GenInfo Identifier: | 48429182 |
| NCBI Gene ID: | 11091 |
| NCBI Accession: | P61964.1 |
| UniProt Secondary Accession: | P61964,Q91VA5, Q9NWX7, Q9UGP9, |
| UniProt Related Accession: | P61964 |
| Molecular Weight: | 36,588 Da |
| NCBI Full Name: | WD repeat-containing protein 5 |
| NCBI Synonym Full Names: | WD repeat domain 5 |
| NCBI Official Symbol: | WDR5 |
| NCBI Official Synonym Symbols: | SWD3; BIG-3; CFAP89 |
| NCBI Protein Information: | WD repeat-containing protein 5 |
| UniProt Protein Name: | WD repeat-containing protein 5 |
| UniProt Synonym Protein Names: | BMP2-induced 3-kb gene protein |
| Protein Family: | WD repeat-containing protein |
| UniProt Gene Name: | WDR5 |
| UniProt Entry Name: | WDR5_HUMAN |
 | Western blot - WDR5 Rabbit mAb (CAB3259) |
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