Cell Biology Antibodies 17

Anti-VTA1 Antibody (CAB18462)

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SKU:
CAB18462
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-VTA1 Antibody
Antibody SKU:CAB18462
Antibody Size:20uL, 50uL, 100uL
Application:IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant protein of human VTA1.
Application:IF
Recommended Dilution:IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:
Immunogen:Recombinant protein of human VTA1.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:51534
Uniprot:Q9NP79
Cellular Location:
Calculated MW:
Observed MW:Refer to figures
Synonyms:C6orf55, DRG-1, DRG1, HSPC228, LIP5, My012, SBP1, VTA1
Background:
UniProt Protein Function:VTA1: Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR. Involved in HIV-1 budding. Belongs to the VTA1 family.
UniProt Protein Details:

Protein type:Unknown function

Chromosomal Location of Human Ortholog: 6q24.1

Cellular Component: endosome membrane; cytosol

Molecular Function:protein binding

Biological Process: protein transport; viral reproduction; viral infectious cycle; endosome transport

NCBI Summary:C6ORF55 encodes a protein involved in trafficking of the multivesicular body, an endosomal compartment involved in sorting membrane proteins for degradation in lysosomes (Ward et al., 2005 [PubMed 15644320]).[supplied by OMIM, Mar 2008]
UniProt Code:Q9NP79
NCBI GenInfo Identifier:30580379
NCBI Gene ID:51534
NCBI Accession:Q9NP79.1
UniProt Related Accession:Q9NP79
Molecular Weight:
NCBI Full Name:Vacuolar protein sorting-associated protein VTA1 homolog
NCBI Synonym Full Names:vesicle trafficking 1
NCBI Official Symbol:VTA1  
NCBI Official Synonym Symbols:DRG1; LIP5; SBP1; DRG-1; My012; C6orf55; HSPC228  
NCBI Protein Information:vacuolar protein sorting-associated protein VTA1 homolog
UniProt Protein Name:Vacuolar protein sorting-associated protein VTA1 homolog
UniProt Synonym Protein Names:Dopamine-responsive gene 1 protein; DRG-1; LYST-interacting protein 5; LIP5; SKD1-binding protein 1; SBP1
Protein Family:Vacuolar protein sorting-associated protein
UniProt Gene Name:VTA1  
UniProt Entry Name:VTA1_HUMAN
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