Anti-VRK3 Antibody (CAB18838)
- SKU:
- CAB18838
Description
| Product Name: | VRK3 Rabbit pAb |
| Product Code: | CAB18838 |
| Size: | 20uL, 50uL, 100uL |
| Applications: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human VRK3. |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | HepG2 |
| Immunogen: | Recombinant protein of human VRK3. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 51231 |
| Uniprot: | Q8IV63 |
| Observed MW: | 53KDa |
| UniProt Protein Function: | Inactive kinase that suppresses ERK activity by promoting phosphatase activity of DUSP3 which specifically dephosphorylates and inactivates ERK in the nucleus. |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. In both human and mouse, this gene has substitutions at several residues within the ATP binding motifs that in other kinases have been shown to be required for catalysis. In vitro assays indicate the protein lacks phosphorylation activity. The protein, however, likely retains its substrate binding capability. This gene is widely expressed in human tissues and its protein localizes to the nucleus. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8IV63 |
| NCBI GenInfo Identifier: | 71164888 |
| NCBI Gene ID: | 51231 |
| NCBI Accession: | NP_001020949.1 |
| UniProt Secondary Accession: | Q8IV63,Q502Y2, Q9P2V8, A6NEG5, A8KA53 |
| UniProt Related Accession: | Q8IV63 |
| Molecular Weight: | 52 kD |
| NCBI Full Name: | inactive serine/threonine-protein kinase VRK3 isoform 2 |
| NCBI Synonym Full Names: | VRK serine/threonine kinase 3 |
| NCBI Official Symbol: | VRK3 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | inactive serine/threonine-protein kinase VRK3 |
| UniProt Protein Name: | Inactive serine/threonine-protein kinase VRK3 |
| UniProt Synonym Protein Names: | Serine/threonine-protein pseudokinase VRK3; Vaccinia-related kinase 3 |
| Protein Family: | Inactive serine/threonine-protein kinase |
| UniProt Gene Name: | VRK3 |
| UniProt Entry Name: |
Additional Information
Product Type: |
Antibody |
Antibody Type: |
Polyclonal Antibody |
Reactivity: |
Human |
Host Species: |
Rabbit |
Isotype: |
IgG |
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