von Willebrand factor (VWF) Monoclonal Antibody (CAB21054)

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SKU:
CAB21054
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Developmental Biology
Reactivity:
Human, Mouse
Synonyms:
VWD, F8VWF, von Willebrand factor (VWF)
Research Use:
Developmental Biology
Frequently bought together:

Description

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von Willebrand factor (VWF) Monoclonal Antibody (CAB21054)

The von Willebrand factor (VWF) Monoclonal Antibody (CAB21054) is a high-quality antibody developed for reliable detection and analysis of target proteins. This polyclonal antibody, produced in rabbits, is highly specific and reactive with human samples, making it ideal for various research applications.Von Willebrand Factor is essential for the normal functioning of the hemostatic system, playing a crucial role in the formation of blood clots and preventing excessive bleeding. Dysregulation of VWF has been implicated in various bleeding disorders, making it a target of interest for researchers in the fields of hematology and vascular biology.

This antibody is validated for use in IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:von Willebrand factor (VWF) Monoclonal Antibody
SKU:CAB21054
Size:20μL, 100μL
Reactivity:Human, Mouse
Clone Number:ARC52173
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:LPTA CTIQ LRGG QIMT LKRD ETLQ DGCD THFC KVNE RGEY FWEK RVTG CPPF DEHK CLAE GGKI MKIP GTCC DTCE EPEC NDIT ARLQ YVKV GSCK SEVE VDIH YCQG KCAS KAMY SIDI NDVQ DQCS CCSP TRTE PMQV ALHC TNGS VVYH EVLN AMEC KCSP RKCS K
Tested Applications:IHC-P ELISA
Recommended Dilution:
IHC-P1:1000 - 1:4000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:VWD, F8VWF, von Willebrand factor (VWF)
Cellular Localization:Secreted, Extracellular Matrix, Extracellular Space.
Calculated MW:309kDa
Observed MW:Refertofigures

This gene encodes a glycoprotein involved in hemostasis. The encoded preproprotein is proteolytically processed following assembly into large multimeric complexes. These complexes function in the adhesion of platelets to sites of vascular injury and the transport of various proteins in the blood. Mutations in this gene result in von Willebrand disease, an inherited bleeding disorder. An unprocessed pseudogene has been found on chromosome 22.

Purification MethodAffinity purification
Gene ID7450
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageImmunohistochemistry analysis of paraffin-embedded Human colon tissue using von Willebrand factor (VWF) Rabbit mAb (CAB21054) at a dilution of 1:600 (40x lens). High pressure antigen retrieval performed with 0.01M Tris-EDTA Buffer (pH 9.0) prior to IHC staining.
Product ImageImmunohistochemistry analysis of paraffin-embedded Human tonsil tissue using von Willebrand factor (VWF) Rabbit mAb (CAB21054) at a dilution of 1:600 (40x lens). High pressure antigen retrieval performed with 0.01M Tris-EDTA Buffer (pH 9.0) prior to IHC staining.
Product ImageImmunohistochemistry analysis of paraffin-embedded Mouse spleen tissue using von Willebrand factor (VWF) Rabbit mAb (CAB21054) at a dilution of 1:600 (40x lens). High pressure antigen retrieval performed with 0.01M Tris-EDTA Buffer (pH 9.0) prior to IHC staining.
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