Developmental Biology
Anti-VIPAS39 Antibody (CAB14918)
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- SKU:
- CAB14918
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Description
| Antibody Name: | Anti-VIPAS39 Antibody |
| Antibody SKU: | CAB14918 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human VIPAS39 (NP_071350.2). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Mouse, Rat |
| Positive Samples: | Mouse liver, Mouse kidney, Mouse brain, Rat heart, Rat liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human VIPAS39 (NP_071350.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MNRT KGDE EEYW NSSK FKAF TFDD EDDE LSQL KESK RAVN SLRD FVDD DDDD DLER VSWS GEPV GSIS WSIR ETAG NSGS THEG REQL KSRN SFSS YAQL PKPT STYS LSSF FRGR TRPG SFQS LSDA LSDT PAKS YAPE LGRP KGEY RDYS NDWS PSDT VRRL RKGK VCSL ERFR SLQD KLQL LEEA VSMH DGNV ITAV LIFL KRTL SKEI LFRE LEVR |
| Gene ID: | 63894 |
| Uniprot: | Q9H9C1 |
| Cellular Location: | Cytoplasm, Cytoplasmic vesicle, Early endosome, Late endosome, Recycling endosome |
| Calculated MW: | 51kDa/57kDa |
| Observed MW: | 57kDa |
| Synonyms: | VIPAS39, C14orf133, SPE-39, SPE39, VIPAR, VPS16B, hSPE-39 |
| Background: | This gene encodes a protein involved in the sorting of lysosomal proteins. Mutations in this gene are associated with ARCS2 (arthrogryposis, renal dysfunction, and cholestasis-2). Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | VIPAS39: a protein of unknown function. Two splice-variant isoforms have been described. |
| UniProt Protein Details: | Protein type:Vesicle Chromosomal Location of Human Ortholog: 14q24.3 Cellular Component: recycling endosome; cytoplasmic membrane-bound vesicle; cytoplasm; early endosome; late endosome Molecular Function:protein binding Biological Process: intracellular protein transport; transcription, DNA-dependent; regulation of transcription, DNA-dependent; endosome to lysosome transport; spermatogenesis; cell differentiation Disease: Arthrogryposis, Renal Dysfunction, And Cholestasis 2 |
| NCBI Summary: | This gene encodes a protein involved in the sorting of lysosomal proteins. Mutations in this gene are associated with ARCS2 (arthrogryposis, renal dysfunction, and cholestasis-2). Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jul 2010] |
| UniProt Code: | Q9H9C1 |
| NCBI GenInfo Identifier: | 41016926 |
| NCBI Gene ID: | 63894 |
| NCBI Accession: | Q9H9C1.1 |
| UniProt Secondary Accession: | Q9H9C1,O95434, Q9H7E1, Q9H9I9, B4DPI6, |
| UniProt Related Accession: | Q9H9C1 |
| Molecular Weight: | 493 |
| NCBI Full Name: | Spermatogenesis-defective protein 39 homolog |
| NCBI Synonym Full Names: | VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog |
| NCBI Official Symbol: | VIPAS39 |
| NCBI Official Synonym Symbols: | SPE39; VIPAR; SPE-39; VPS16B; hSPE-39; C14orf133 |
| NCBI Protein Information: | spermatogenesis-defective protein 39 homolog; protein spe-39 homolog; VPS33B-interacting protein in polarity and apical restriction; VPS33B-interacting protein in apical-basolateral polarity regulator; VPS33B-interacting protein involved in polarity and apical protein restriction |
| UniProt Protein Name: | Spermatogenesis-defective protein 39 homolog |
| UniProt Synonym Protein Names: | VPS33B-interacting protein in apical-basolateral polarity regulator; VPS33B-interacting protein in polarity and apical restriction |
| Protein Family: | Spermatogenesis-defective protein |
| UniProt Gene Name: | VIPAS39 |
| UniProt Entry Name: | SPE39_HUMAN |
 | Western blot analysis of extracts of various cell lines, using VIPAS39 Rabbit pAb (CAB14918) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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