Developmental Biology

Anti-VAMP5 Antibody (CAB14371)

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SKU:
CAB14371
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Developmental Biology

Description

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Antibody Name:Anti-VAMP5 Antibody
Antibody SKU:CAB14371
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-116 of human VAMP5 (NP_006625.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse
Positive Samples:Mouse spleen
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-116 of human VAMP5 (NP_006625.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MAGI ELER CQQQ ANEV TEIM RNNF GKVL ERGV KLAE LQQR SDQL LDMS STFN KTTQ NLAQ KKCW ENIR YRIC VGLV VVGV LLII LIVL LVVF LPQS SDSS SAPR TQDA GIAS GPGN
Gene ID:10791
Uniprot:O95183
Cellular Location:Cell membrane, Endomembrane system, Golgi apparatus, Single-pass type IV membrane protein, trans-Golgi network membrane
Calculated MW:12kDa
Observed MW:16kDa
Synonyms:VAMP5
Background:Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of vesicles and cell membranes. The VAMP5 gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family and the SNARE superfamily. This VAMP family member may participate in vesicle trafficking events that are associated with myogenesis.
UniProt Protein Function:VAMP5: May participate in trafficking events that are associated with myogenesis, such as myoblast fusion and/or GLUT4 trafficking. Belongs to the synaptobrevin family.
UniProt Protein Details:

Protein type:Membrane protein, integral

Chromosomal Location of Human Ortholog: 2p11.2

Cellular Component: SNARE complex; synaptic vesicle; cytoplasmic vesicle membrane; cell surface; perinuclear region of cytoplasm; integral to plasma membrane; late endosome; plasma membrane; trans-Golgi network

Molecular Function:SNAP receptor activity; SNARE binding

Biological Process: vesicle fusion; muscle development; skeletal muscle development; exocytosis; neurotransmitter secretion; Golgi to plasma membrane protein transport; cell differentiation

NCBI Summary:Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of vesicles and cell membranes. The VAMP5 gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family and the SNARE superfamily. This VAMP family member may participate in vesicle trafficking events that are associated with myogenesis. [provided by RefSeq, Jul 2008]
UniProt Code:O95183
NCBI GenInfo Identifier:5730112
NCBI Gene ID:10791
NCBI Accession:NP_006625.1
UniProt Secondary Accession:O95183,Q9P0T2,
UniProt Related Accession:O95183
Molecular Weight:12,805 Da
NCBI Full Name:vesicle-associated membrane protein 5
NCBI Synonym Full Names:vesicle-associated membrane protein 5
NCBI Official Symbol:VAMP5  
NCBI Protein Information:vesicle-associated membrane protein 5; VAMP-5; myobrevin
UniProt Protein Name:Vesicle-associated membrane protein 5
UniProt Synonym Protein Names:Myobrevin
Protein Family:Vesicle-associated membrane protein
UniProt Gene Name:VAMP5  
UniProt Entry Name:VAMP5_HUMAN
Anti-VAMP5 Antibody (CAB14371)Western blot analysis of extracts of mouse spleen, using VAMP5 antibody (CAB14371) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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