Anti-USP11 Antibody (CAB20179)
- SKU:
- CAB20179
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- UHX1
Description
| Product Name: | USP11 Rabbit pAb |
| Product Code: | CAB20179 |
| Size: | 50uL, 100uL |
| Synonyms: | UHX1 |
| Applications: | WB, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant protein of human USP11. |
| Applications: | WB, IF |
| Recommended Dilutions: | WB 1:1000 - 1:2000 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, 293T, Jurkat, Rat testis |
| Immunogen: | Recombinant protein of human USP11. |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 8237 |
| Uniprot: | P51784 |
| Calculated MW: | 110kDa |
| Observed MW: | 110KDa |
| UniProt Protein Function: | USP11: Protease that can remove conjugated ubiquitin from target proteins and polyubiquitin chains. Inhibits the degradation of target proteins by the proteasome. Plays a role in the regulation of pathways leading to NF-kappa-B activation. Plays a role in the regulation of DNA repair after double-stranded DNA breaks. Belongs to the peptidase C19 family.Protein type: EC 3.4.19.12; Ubiquitin conjugating system; Ubiquitin-specific protease; ProteaseChromosomal Location of Human Ortholog: Xp11.23Cellular Component: cytoplasm; nucleusMolecular Function: protein binding; cysteine-type endopeptidase activity; ubiquitin-specific protease activityBiological Process: proteasomal ubiquitin-dependent protein catabolic process; protein deubiquitination |
| UniProt Protein Details: | |
| NCBI Summary: | Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This gene encodes a deubiquitinating enzyme which lies in a gene cluster on chromosome Xp11.23 [provided by RefSeq, Jul 2008] |
| UniProt Code: | P51784 |
| NCBI GenInfo Identifier: | 251757432 |
| NCBI Gene ID: | 8237 |
| NCBI Accession: | P51784.3 |
| UniProt Secondary Accession: | P51784,Q8IUG6, Q9BWE1, B2RTX1 |
| UniProt Related Accession: | P51784 |
| Molecular Weight: | 110kDa |
| NCBI Full Name: | Ubiquitin carboxyl-terminal hydrolase 11 |
| NCBI Synonym Full Names: | ubiquitin specific peptidase 11 |
| NCBI Official Symbol: | USP11 |
| NCBI Official Synonym Symbols: | UHX1 |
| NCBI Protein Information: | ubiquitin carboxyl-terminal hydrolase 11; ubiquitin thioesterase 11; deubiquitinating enzyme 11; ubiquitin thiolesterase 11; ubiquitin-specific processing protease 11; ubiquitin-specific-processing protease 11; ubiquitin carboxyl-terminal hydrolase, X-linked |
| UniProt Protein Name: | Ubiquitin carboxyl-terminal hydrolase 11 |
| UniProt Synonym Protein Names: | Deubiquitinating enzyme 11; Ubiquitin thioesterase 11; Ubiquitin-specific-processing protease 11 |
| Protein Family: | Ubiquitin carboxyl-terminal hydrolase |
| UniProt Gene Name: | USP11 |
| UniProt Entry Name: | UBP11_HUMAN |
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