Cell Biology Antibodies 17
Anti-UQCRC2 Antibody (CAB4366)
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- SKU:
- CAB4366
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- MC3DN5
- Synonyms:
- QCR2
- Synonyms:
- UQCR2
- Research Area:
- Cell Biology
Description
| Product Name: | UQCRC2 Rabbit mAb |
| Product Code: | CAB4366 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | MC3DN5, QCR2, UQCR2 |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human UQCRC2 |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | 293T, HepG2, A-549, Mouse heart, Rat brain, Rat heart |
| Immunogen: | A synthesized peptide derived from human UQCRC2 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 7385 |
| Uniprot: | P22695 |
| Cellular Location: | Matrix side, Mitochondrion inner membrane, Peripheral membrane protein |
| Calculated MW: | 48kDa |
| Observed MW: | 48KDa |
| UniProt Protein Function: | UQCRC2: This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex. Belongs to the peptidase M16 family. UQCRC2/QCR2 subfamily. |
| UniProt Protein Details: | Protein type:EC 1.10.2.2; Mitochondrial; Oxidoreductase; Energy Metabolism - oxidative phosphorylation Chromosomal Location of Human Ortholog: 16p12 Cellular Component: mitochondrion; mitochondrial inner membrane; mitochondrial respiratory chain complex III Molecular Function:protein binding; metal ion binding; metalloendopeptidase activity; protein complex binding Biological Process: cellular metabolic process; aerobic respiration; proteolysis; oxidative phosphorylation Disease: Mitochondrial Complex Iii Deficiency, Nuclear Type 5 |
| NCBI Summary: | The protein encoded by this gene is located in the mitochondrion, where it is part of the ubiquinol-cytochrome c reductase complex (also known as complex III). This complex constitutes a part of the mitochondrial respiratory chain. Defects in this gene are a cause of mitochondrial complex III deficiency nuclear type 5. [provided by RefSeq, Jul 2015] |
| UniProt Code: | P22695 |
| NCBI GenInfo Identifier: | 21903482 |
| NCBI Gene ID: | 7385 |
| NCBI Accession: | P22695.3 |
| UniProt Secondary Accession: | P22695,Q9DB77, P32551, |
| UniProt Related Accession: | P22695 |
| Molecular Weight: | 48kDa |
| NCBI Full Name: | Cytochrome b-c1 complex subunit 2, mitochondrial |
| NCBI Synonym Full Names: | ubiquinol-cytochrome c reductase core protein 2 |
| NCBI Official Symbol: | UQCRC2 |
| NCBI Official Synonym Symbols: | QCR2; UQCR2; MC3DN5 |
| NCBI Protein Information: | cytochrome b-c1 complex subunit 2, mitochondrial |
| UniProt Protein Name: | Cytochrome b-c1 complex subunit 2, mitochondrial |
| UniProt Synonym Protein Names: | Complex III subunit 2; Core protein II; Ubiquinol-cytochrome-c reductase complex core protein 2 |
| UniProt Gene Name: | UQCRC2 |
| UniProt Entry Name: | QCR2_HUMAN |
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