Cell Biology Antibodies 8
Anti-UQCRC1 Antibody (CAB3339)
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- SKU:
- CAB3339
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-UQCRC1 Antibody |
| Antibody SKU: | CAB3339 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 156-480 of human UQCRC1 (NP_003356.2). |
| Application: | WB IHC |
| Recommended Dilution: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | A-549, HepG2, HeLa, 293T, COS-7, Mouse liver, Rat brain, Rat spinal cord |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 156-480 of human UQCRC1 (NP_003356.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | LEDS QIEK ERDV ILRE MQEN DASM RDVV FNYL HATA FQGT PLAQ AVEG PSEN VRKL SRAD LTEY LSTH YKAP RMVL AAAG GVEH QQLL DLAQ KHLG GIPW TYAE DAVP TLTP CRFT GSEI RHRD DALP FAHV AIAV EGPG WASP DNVA LQVA NAII GHYD CTYG GGVH LSSP LASG AVAN KLCQ SFQT FSIC YAET GLLG AHFV CDRM KIDD MMFV LQGQ WMRL CTSA TESE VARG KNIL RNAL VSHL DGTT PVCE DIGR SLLT YGRR IPLA EWES RIAE VDAS VVRE ICSK YIYD QCPA VAGY GPIE QLPD YNRI RSGM FWLR F |
| Gene ID: | 7384 |
| Uniprot: | P31930 |
| Cellular Location: | Mitochondrion inner membrane |
| Calculated MW: | 52kDa |
| Observed MW: | 53kDa |
| Synonyms: | UQCRC1, D3S3191, QCR1, UQCR1 |
| Background: |
| UniProt Protein Function: | UQCRC1: This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the peptidase M16 family. UQCRC1/QCR1 subfamily. |
| UniProt Protein Details: | Protein type:Mitochondrial; Energy Metabolism - oxidative phosphorylation; EC 1.10.2.2; Oxidoreductase Chromosomal Location of Human Ortholog: 3p21.3 Cellular Component: mitochondrion; mitochondrial inner membrane; mitochondrial respiratory chain complex III; mitochondrial respiratory chain Molecular Function:metal ion binding; ubiquinol-cytochrome-c reductase activity; protein complex binding Biological Process: response to alkaloid; cellular metabolic process; aerobic respiration; response to activity; oxidative phosphorylation; mitochondrial electron transport, ubiquinol to cytochrome c |
| UniProt Code: | P31930 |
| NCBI GenInfo Identifier: | 92090651 |
| NCBI Gene ID: | 7384 |
| NCBI Accession: | P31930.3 |
| UniProt Secondary Accession: | P31930,Q96DD2, B2R7R8, |
| UniProt Related Accession: | P31930 |
| Molecular Weight: | 52,646 Da |
| NCBI Full Name: | Cytochrome b-c1 complex subunit 1, mitochondrial |
| NCBI Synonym Full Names: | ubiquinol-cytochrome c reductase core protein I |
| NCBI Official Symbol: | UQCRC1 |
| NCBI Official Synonym Symbols: | QCR1; UQCR1; D3S3191 |
| NCBI Protein Information: | cytochrome b-c1 complex subunit 1, mitochondrial; core protein I; complex III subunit 1; ubiquinol-cytochrome-c reductase complex core protein 1 |
| UniProt Protein Name: | Cytochrome b-c1 complex subunit 1, mitochondrial |
| UniProt Synonym Protein Names: | Complex III subunit 1; Core protein I; Ubiquinol-cytochrome-c reductase complex core protein 1 |
| UniProt Gene Name: | UQCRC1 |
| UniProt Entry Name: | QCR1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using UQCRC1 antibody (CAB3339) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
 | Immunohistochemistry of paraffin-embedded human colon using UQCRC1 Rabbit pAb (CAB3339) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse kidney using UQCRC1 Rabbit pAb (CAB3339) at dilution of 1:100 (40x lens). |
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