Name: Anti-UQCC2 Antibody (CAB9986)
Brand: Cell Biology Antibodies 16
SKU: CAB9986
Availability: OutOfStock

Antibody Name:	Anti-UQCC2 Antibody
Antibody SKU:	CAB9986
Antibody Size:	20uL, 50uL, 100uL
Application:	WB IHC IF
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 14-126 of human UQCC2 (NP_115716.1).

Application:	WB IHC IF
Recommended Dilution:	WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:	Human, Mouse, Rat
Positive Samples:	MCF7, THP-1, HepG2, U-251MG, Mouse heart, Mouse brain, Mouse testis, Rat brain

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 14-126 of human UQCC2 (NP_115716.1).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	EEWP VDET KRGR DLGA YLRQ RVAQ AFRE GENT QVAE PEAC DQMY ESLA RLHS NYYK HKYP RPRD TSFS GLSL EEYK LILS TDTL EELK EIDK GMWK KLQE KFAP KGPE EDHK A
Gene ID:	84300
Uniprot:	Q9BRT2
Cellular Location:	Mitochondrion, Mitochondrion inner membrane, Mitochondrion intermembrane space, Mitochondrion matrix, mitochondrion nucleoid
Calculated MW:	14kDa
Observed MW:	15kDa

Synonyms:	UQCC2, C6orf125, C6orf126, Cbp6, M19, MNF1, bA6B20.2
Background:	This gene encodes a nucleoid protein localized to the mitochondria inner membrane. The encoded protein affects regulation of insulin secretion, mitochondrial ATP production, and myogenesis through modulation of mitochondrial respiratory chain activity.

UniProt Protein Function:	UQCC2: Plays a role in the modulation of respiratory chain activities such as oxygen consumption and ATP production and via its modulation of the respiratory chain activity can regulate skeletal muscle differentiation and insulin secretion by pancreatic beta-cells
UniProt Protein Details:	Protein type:Mitochondrial Chromosomal Location of Human Ortholog: 6p21.31 Cellular Component: mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrial matrix; mitochondrion; nuclear body Molecular Function:protein binding Biological Process: regulation of insulin secretion; regulation of oxidative phosphorylation Disease: Mitochondrial Complex Iii Deficiency, Nuclear Type 7
NCBI Summary:	This gene encodes a nucleoid protein localized to the mitochondria inner membrane. The encoded protein affects regulation of insulin secretion, mitochondrial ATP production, and myogenesis through modulation of mitochondrial respiratory chain activity. [provided by RefSeq, Oct 2012]
UniProt Code:	Q9BRT2
NCBI GenInfo Identifier:	73917719
NCBI Gene ID:	84300
NCBI Accession:	Q9BRT2.1
UniProt Secondary Accession:	Q9BRT2,B2R4I0,
UniProt Related Accession:	Q9BRT2
Molecular Weight:	15kDa
NCBI Full Name:	Ubiquinol-cytochrome-c reductase complex assembly factor 2
NCBI Synonym Full Names:	ubiquinol-cytochrome c reductase complex assembly factor 2
NCBI Official Symbol:	UQCC2
NCBI Official Synonym Symbols:	M19; Cbp6; MNF1; C6orf125; C6orf126; bA6B20.2
NCBI Protein Information:	ubiquinol-cytochrome-c reductase complex assembly factor 2
UniProt Protein Name:	Ubiquinol-cytochrome-c reductase complex assembly factor 2
UniProt Synonym Protein Names:	Breast cancer-associated protein SGA-81M; Mitochondrial nucleoid factor 1; Mitochondrial protein M19
Protein Family:	Ubiquinol-cytochrome-c reductase complex assembly factor
UniProt Gene Name:	UQCC2

	Western blot analysis of extracts of various cell lines, using UQCC2 antibody (CAB9986) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s.
	Immunohistochemistry of paraffin-embedded rat spleen using UQCC2 antibody (CAB9986) at dilution of 1:100 (40x lens).
	Immunohistochemistry of paraffin-embedded rat heart using UQCC2 antibody (CAB9986) at dilution of 1:100 (40x lens).
	Immunohistochemistry of paraffin-embedded mouse heart using UQCC2 antibody (CAB9986) at dilution of 1:100 (40x lens).