Cell Biology Antibodies 16

Anti-Uhrf2 Antibody (CAB2344)

(No reviews yet) Write a Review
SKU:
CAB2344
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-Uhrf2 Antibody
Antibody SKU:CAB2344
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 76-359 of mouse Uhrf2 (NP_659122.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:Jurkat, U-87MG, HeLa, Mouse liver, Rat thymus
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 76-359 of mouse Uhrf2 (NP_659122.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:DSSL PSTS KQND AQVK PSSH NPPK VKKT ARGG SSSQ PSTS ARTC LIDP GFGL YKVN ELVD ARDV GLGA WFEA HIHS VTRA SDGH SRGK TPLK NGSS YKRT NGNV NHNS KENT NKLD NVPS TSNS DSVA ADED VIYH IEYD EYPE SGIL EMNV KDLR PRAR TILK WNEL NVGD VVMV NYNV ENPG KRGF WYDA EITT LKTI SRTK KEVR VKVF LGGS EGTL NDCR VMSV DEIF KIEK PGAH PISF ADGK FLRK NDPE CDLC GGDP DKTC HMCS CHKC GEKR DPNM
Gene ID:109113
Uniprot:
Cellular Location:Nucleus
Calculated MW:56kDa/89kDa
Observed MW:110kDa
Synonyms:UHRF2, NIRF, RNF107, TDRD23, URF2, Uhrf2
Background:This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding.
Anti-Uhrf2 Antibody (CAB2344)Western blot analysis of extracts of various cell lines, using UHRF2 antibody (CAB2344) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
View AllClose

0 Reviews

View AllClose

Related Products