Cell Death Antibodies 1
Anti-TP53AIP1 Antibody (CAB14146)
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- SKU:
- CAB14146
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Description
| Antibody Name: | Anti-TP53AIP1 Antibody |
| Antibody SKU: | CAB14146 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-108 of human TP53AIP1 (NP_001238893.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | 5637, HepG2, U-937, HT-29 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-108 of human TP53AIP1 (NP_001238893.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MGSS SEAS FRSA QASC SGAR RQGL GRGD QNLS VMPP NGRA QTHT PGWV SPCS ENRD GLLP ATAP GRLC SHRG ADIP SFQT HQDP VTAS GSSE LHAD CPQF RALD RAGN |
| Gene ID: | 63970 |
| Uniprot: | Q9HCN2 |
| Cellular Location: | Mitochondrion |
| Calculated MW: | 8kDa/11kDa/12kDa |
| Observed MW: | 13kDa |
| Synonyms: | TP53AIP1, P53AIP1 |
| Background: | This gene is specifically expressed in the thymus, and encodes a protein that is localized to the mitochondrion. The expression of this gene is inducible by p53, and it is thought to play an important role in mediating p53-dependent apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
| UniProt Protein Function: | p53AIP1: May play an important role in mediating p53/TP53- dependent apoptosis. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Mitochondrial; Apoptosis Chromosomal Location of Human Ortholog: 11q24 Cellular Component: mitochondrion Biological Process: apoptosis |
| NCBI Summary: | This gene is specifically expressed in the thymus, and encodes a protein that is localized to the mitochondrion. The expression of this gene is inducible by p53, and it is thought to play an important role in mediating p53-dependent apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011] |
| UniProt Code: | Q9HCN2 |
| NCBI GenInfo Identifier: | 74718882 |
| NCBI Gene ID: | 63970 |
| NCBI Accession: | Q9HCN2.1 |
| UniProt Secondary Accession: | Q9HCN2,Q6NT40, Q7Z6F7, Q9HCN0, Q9HCN1, |
| UniProt Related Accession: | Q9HCN2 |
| Molecular Weight: | 124 |
| NCBI Full Name: | p53-regulated apoptosis-inducing protein 1 |
| NCBI Synonym Full Names: | tumor protein p53 regulated apoptosis inducing protein 1 |
| NCBI Official Symbol: | TP53AIP1 |
| NCBI Official Synonym Symbols: | P53AIP1 |
| NCBI Protein Information: | p53-regulated apoptosis-inducing protein 1 |
| UniProt Protein Name: | p53-regulated apoptosis-inducing protein 1 |
| Protein Family: | p53-regulated apoptosis-inducing protein |
| UniProt Gene Name: | TP53AIP1 |
| UniProt Entry Name: | TPIP1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using TP53AIP1 antibody (CAB14146) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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