Developmental Biology
Anti-TNP2 Antibody (CAB6773)
- SKU:
- CAB6773
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Description
| Antibody Name: | Anti-TNP2 Antibody |
| Antibody SKU: | CAB6773 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IF |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-138 of human TNP2 (NP_005416.1). |
| Application: | WB IF |
| Recommended Dilution: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-138 of human TNP2 (NP_005416.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MDTQ THSL PITH TQLH SNSQ PQSR TCTR HCQT FSQS CRQS HRGS RSQS SSQS PASH RNPT GAHS SSGH QSQS PNTS PPPK RHKK TMNS HHSP MRPT ILHC RCPK NRKN LEGK LKKK KMAK RIQQ VYKT KTRS SGWK SN |
| Gene ID: | 7142 |
| Uniprot: | Q05952 |
| Cellular Location: | Chromosome, Nucleus |
| Calculated MW: | 15kDa |
| Observed MW: | Refer to Figures |
| Synonyms: | TNP2, TP2 |
| Background: |
| UniProt Protein Function: | TP2: In the elongating spermatids of mammals, the conversion of nucleosomal chromatin to the compact, non-nucleosomal form found in the sperm nucleus is associated with the appearance of a small set of basic chromosomal transition proteins. Belongs to the nuclear transition protein 2 family. |
| UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 16p13.13 Cellular Component: nucleosome; nucleus Molecular Function:DNA binding; metal ion binding Biological Process: sperm motility; binding of sperm to zona pellucida; multicellular organismal development; acrosome reaction; penetration of zona pellucida; spermatogenesis; cell differentiation |
| UniProt Code: | Q05952 |
| NCBI GenInfo Identifier: | 464818 |
| NCBI Gene ID: | 7142 |
| NCBI Accession: | Q05952.1 |
| UniProt Secondary Accession: | Q05952,Q9NZB0, |
| UniProt Related Accession: | Q05952 |
| Molecular Weight: | 138 |
| NCBI Full Name: | Nuclear transition protein 2 |
| NCBI Synonym Full Names: | transition protein 2 (during histone to protamine replacement) |
| NCBI Official Symbol: | TNP2 |
| NCBI Official Synonym Symbols: | TP2 |
| NCBI Protein Information: | nuclear transition protein 2; TP-2 |
| UniProt Protein Name: | Nuclear transition protein 2 |
| Protein Family: | Nuclear transition protein |
| UniProt Gene Name: | TNP2 |
| UniProt Entry Name: | STP2_HUMAN |
 | Immunofluorescence analysis of U2OS cells using TNP2 antibody (CAB6773). Blue: DAPI for nuclear staining. |
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