Immunology Antibodies 1

TLR8 Rabbit Polyclonal Antibody (CAB1489)

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SKU:
CAB1489
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology
Reactivity:
Human, Mouse, Rat
Synonyms:
CD288, IMD98, hTLR8, TLR8
Research Use:
Immunology
Frequently bought together:

Description

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TLR8 Antibody (CAB1489)

The TLR8 Antibody (CAB1489) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to TLR8 protein, this antibody allows for precise detection and analysis of TLR8 expression in various cell types, making it essential for research in immunology and infectious diseases.TLR8 is known for its role in recognizing single-stranded RNA from viruses and activating the immune response to combat infections.

This antibody is validated for use in WB, IHC-P, ELISA, IF-P applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:TLR8 Antibody
SKU:CAB1489
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:HHLF YWDV WFIY NVCL AKVK GYRS LSTS QTFY DAYI SYDT KDAS VTDW VINE LRYH LEES RDKN VLLC LEER DWDP GLAI IDNL MQSI NQSK KTVF VLTK KYAK SWNF KTAF YLAL QRLM DENM DVII FILL EPVL QHSQ YLRL RQRI CKSS ILQW PDNP KAEG LFWQ TLRN VVLT ENDS RYNN MYVD SIKQ Y
Tested Applications:WB IHC-P ELISA IF-P
Recommended Dilution:
WB1:500 - 1:1000
IF-P1:50 - 1:200
IHC-P1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:CD288, IMD98, hTLR8, TLR8
Positive Sample:HepG2
Cellular Localization:Membrane, Single-Pass Type I Membrane Protein.
Calculated MW:120kDa
Observed MW:150kDa

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.

Purification MethodAffinity purification
Gene ID51311
RRIDAB_2761770
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from HepG2 cells, using TLR8 Rabbit pAb (CAB1489) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Human colon using TLR8 Rabbit pAb (CAB1489) at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate buffer (pH 6.0) prior to IHC staining.
Product ImageImmunohistochemistry analysis of paraffin-embedded Human lung cancer using TLR8 Rabbit pAb (CAB1489) at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate buffer (pH 6.0) prior to IHC staining.
Product ImageImmunofluorescence analysis of paraffin-embedded rat spleen using TLR8 Rabbit pAb (CAB1489) at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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