Developmental Biology

Anti-THOC5 Antibody (CAB11635)

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SKU:
CAB11635
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Developmental Biology

Description

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Antibody Name:Anti-THOC5 Antibody
Antibody SKU:CAB11635
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 150-370 of human THOC5 (NP_003669.4).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:HT-29, Mouse testis, Rat testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 150-370 of human THOC5 (NP_003669.4).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:FKSK HEEI DLVS LEEF YKEA PPDI SKAE VTMG DPHQ QTLA RLDW ELEQ RKRL AEKY RECL SNKE KILK EIEV KKEY LSSL QPRL NSIM QASL PVQE YLFM PFDQ AHKQ YETA RHLP PPLY VLFV QATA YGQA CDKT LSVA IEGS VDEA KALF KPPE DSQD DESD SDAE EEQT TKRR RPTL GVQL DDKR KEML KRHP LSVM LDLK CKDD SVLH LTFY YLMN L
Gene ID:8563
Uniprot:Q13769
Cellular Location:Cytoplasm, Nucleus, Nucleus speckle
Calculated MW:78kDa
Observed MW:78kDa
Synonyms:THOC5, C22orf19, Fmip, PK1.3, fSAP79
Background:
UniProt Protein Function:FMIP: a Fms-interacting protein. Binds transiently to activated Fms. Phosphorylation by protein kinase C has been reported to potentiates M-CSF-mediated differentiation. Overexpression inhibited M-CSF induced macrophage differentiation and enhanced granulocytic differentiation.
UniProt Protein Details:

Protein type:Cell development/differentiation; RNA splicing; Spliceosome

Chromosomal Location of Human Ortholog: 22q12.2

Cellular Component: nuclear chromosome, telomeric region; nucleoplasm; nucleus

Molecular Function:mRNA binding; protein binding

Biological Process: intronless viral mRNA export from host nucleus; monocyte differentiation; mRNA 3'-end processing; mRNA export from nucleus; positive regulation of RNA elongation; RNA export from nucleus; termination of RNA polymerase II transcription

UniProt Code:Q13769
NCBI GenInfo Identifier:259016156
NCBI Gene ID:8563
NCBI Accession:Q13769.2
UniProt Secondary Accession:Q13769,O60839, Q9UPZ5,
UniProt Related Accession:Q13769
Molecular Weight:79kDa
NCBI Full Name:THO complex subunit 5 homolog
NCBI Synonym Full Names:THO complex 5
NCBI Official Symbol:THOC5  
NCBI Official Synonym Symbols:Fmip; PK1.3; fSAP79; C22orf19  
NCBI Protein Information:THO complex subunit 5 homolog
UniProt Protein Name:THO complex subunit 5 homolog
UniProt Synonym Protein Names:Functional spliceosome-associated protein 79; fSAP79; NF2/meningioma region protein pK1.3; Placental protein 39.2; PP39.2; hTREX90
Protein Family:THO complex
UniProt Gene Name:THOC5  
Anti-THOC5 Antibody (CAB11635)Western blot analysis of extracts of various cell lines, using THOC5 antibody (CAB11635) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s.
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