Epigenetics & Nuclear Signaling Antibodies 2

Anti-TFB1M Antibody (CAB15231)

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SKU:
CAB15231
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling

Description

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Antibody Name:Anti-TFB1M Antibody
Antibody SKU:CAB15231
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 28-346 of human TFB1M (NP_057104.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:293T, A-549, MCF7, Mouse kidney, Rat heart
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 28-346 of human TFB1M (NP_057104.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:QAAK QLSQ NFLL DLRL TDKI VRKA GNLT NAYV YEVG PGPG GITR SILN ADVA ELLV VEKD TRFI PGLQ MLSD AAPG KLRI VHGD VLTF KVEK AFSE SLKR PWED DPPN VHII GNLP FSVS TPLI IKWL ENIS CRDG PFVY GRTQ MTLT FQKE VAER LAAN TGSK QRSR LSVM AQYL CNVR HIFT IPGQ AFVP KPEV DVGV VHFT PLIQ PKIE QPFK LVEK VVQN VFQF RRKY CHRG LRML FPEA QRLE STGR LLEL ADID PTLR PRQL SISH FKSL CDVY RKMC DEDP QLFA YNFR EELK RRKS KNEE KEED DAEN YRL
Gene ID:51106
Uniprot:Q8WVM0
Cellular Location:Mitochondrion
Calculated MW:39kDa
Observed MW:40KDa
Synonyms:TFB1M, CGI-75, CGI75, mtTFB, mtTFB1
Background:The protein encoded by this gene is a dimethyltransferase that methylates the conserved stem loop of mitochondrial 12S rRNA. The encoded protein also is part of the basal mitochondrial transcription complex and is necessary for mitochondrial gene expression. The methylation and transcriptional activities of this protein are independent of one another. Variations in this gene may influence the severity of aminoglycoside-induced deafness (AID).
NCBI Summary:The protein encoded by this gene is a dimethyltransferase that methylates the conserved stem loop of mitochondrial 12S rRNA. The encoded protein also is part of the basal mitochondrial transcription complex and is necessary for mitochondrial gene expression. The methylation and transcriptional activities of this protein are independent of one another. Variations in this gene may influence the severity of aminoglycoside-induced deafness (AID).[provided by RefSeq, Aug 2010]
UniProt Code:Q8WVM0
NCBI GenInfo Identifier:17389499
NCBI Gene ID:51106
NCBI Accession:BC017788
UniProt Secondary Accession:Q8WVM0,Q05DR0, Q9Y384,
UniProt Related Accession:Q8WVM0
Molecular Weight:39,543 Da
NCBI Full Name:Homo sapiens transcription factor B1, mitochondrial, mRNA
NCBI Synonym Full Names:transcription factor B1, mitochondrial
NCBI Official Symbol:TFB1M  
NCBI Official Synonym Symbols:CGI75; mtTFB; CGI-75; mtTFB1  
NCBI Protein Information:dimethyladenosine transferase 1, mitochondrial
UniProt Protein Name:
Protein Family:Dimethyladenosine transferase
UniProt Gene Name:
Anti-TFB1M Antibody (CAB15231)Western blot analysis of extracts of various cell lines, using TFB1M antibody (CAB15231) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s.
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