Developmental Biology

Anti-TDRKH Antibody (CAB6767)

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SKU:
CAB6767
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Developmental Biology

Description

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Antibody Name:Anti-TDRKH Antibody
Antibody SKU:CAB6767
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 36-355 of human TDRKH (NP_001077432.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:293T, HepG2, MCF7, SKOV3, Mouse testis, Rat testis
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 36-355 of human TDRKH (NP_001077432.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:RYRE SREE RLTF VGED DIEI EMRV PQEA VKLI IGRQ GANI KQLR KQTG ARID VDTE DVGD ERVL LISG FPVQ VCKA KAAI HQIL TENT PVSE QLSV PQRS VGRI IGRG GETI RSIC KASG AKIT CDKE SEGT LLLS RLIK ISGT QKEV AAAK HLIL EKVS EDEE LRKR IAHS AETR VPRK QPIS VRRE DMTE PGGA GEPA LWKN TSSS MEPT APLV TPPP KGGG DMAV VVSK EGSW EKPS DDSF QKSE AQAI PEMP MFEI PSPD FSFH ADEY LEVY VSAS EHPN HFWI QIVG SRSL QLDK LVNE MTQH YENS VPED LTVH
Gene ID:11022
Uniprot:Q9Y2W6
Cellular Location:Cytoplasm, Mitochondrion
Calculated MW:57kDa/62kDa
Observed MW:72kDa
Synonyms:TDRKH, TDRD2
Background:
UniProt Protein Function:TDRKH: a protein containing one Tudor and two KH_1 domims. Tudor domains have been shown to interact with arginine-glycine-rich motifs in a methylarginine-dependent manner, and target methylated arginines physiologically. KH domains are RNA-binding domains found in a wide variety of nucleic acid-binding proteins. Two isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Unknown function

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: mitochondrion

Molecular Function:RNA binding

Biological Process: fertilization; DNA methylation during gametogenesis; RNA-mediated gene silencing; gene expression; spermatogenesis; cell differentiation; male meiosis

UniProt Code:Q9Y2W6
NCBI GenInfo Identifier:332278122
NCBI Gene ID:11022
NCBI Accession:Q9Y2W6.2
UniProt Related Accession:Q9Y2W6
Molecular Weight:72kDa
NCBI Full Name:Tudor and KH domain-containing protein
NCBI Synonym Full Names:tudor and KH domain containing
NCBI Official Symbol:TDRKH  
NCBI Official Synonym Symbols:TDRD2  
NCBI Protein Information:tudor and KH domain-containing protein
UniProt Protein Name:Tudor and KH domain-containing protein
UniProt Synonym Protein Names:Tudor domain-containing protein 2
Protein Family:Tudor and KH domain-containing protein
UniProt Gene Name:TDRKH  
UniProt Entry Name:TDRKH_HUMAN
Anti-TDRKH Antibody (CAB6767)Western blot analysis of extracts of various cell lines, using TDRKH antibody (CAB6767) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s.
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