Developmental Biology
Anti-TDRD9 Antibody (CAB16592)
- SKU:
- CAB16592
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Description
| Antibody Name: | Anti-TDRD9 Antibody |
| Antibody SKU: | CAB16592 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 300-600 of human TDRD9 (NP_694591.2). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse, Rat |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 300-600 of human TDRD9 (NP_694591.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | AVPV QNKM NPAY IFEV EGKP HSVE EYYL NDLE HIHH SKLS PHLL EEPV ITKD IYEV AVSL IQMF DDLD MKES GNKA WSGA QFVL ERSS VLVF LPGL GEIN YMHE LLTS LVHK RLQV YPLH SSVA LEEQ NNVF LSPV PGYR KIIL STNI AESS VTVP DVKY VIDF CLTR TLVC DEDT NYQS LRLS WASK TSCN QRKG RAGR VSRG YCYR LVHK DFWD NSIP DHVV PEML RCPL GSTI LKVK LLDM GEPR ALLA TALS PPGL SDIE RTIL LLKE VGAL AVSG QRED ENPH DGEL TFLG RVLA Q |
| Gene ID: | 122402 |
| Uniprot: | Q8NDG6 |
| Cellular Location: | Cytoplasm, Nucleus |
| Calculated MW: | 134kDa/155kDa |
| Observed MW: | Refer to figures |
| Synonyms: | TDRD9, C14orf75, HIG-1, NET54 |
| Background: |
| UniProt Protein Function: | TDRD9: Probable ATP-binding RNA helicase which plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with PIWIL4 and the piP-bodies suggests a participation in the secondary piRNAs metabolic process. Belongs to the DEAD box helicase family. DEAH subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Helicase; EC 3.6.4.13 Chromosomal Location of Human Ortholog: 14q32.33 Cellular Component: nucleus Molecular Function:ATP binding; ATP-dependent RNA helicase activity Biological Process: cell differentiation; DNA methylation during gametogenesis; fertilization; gene expression; male meiosis; multicellular organismal development; RNA processing; RNA-mediated gene silencing; spermatogenesis |
| UniProt Code: | Q8NDG6 |
| NCBI GenInfo Identifier: | 166851804 |
| NCBI Gene ID: | 122402 |
| NCBI Accession: | NP_694591.2 |
| UniProt Secondary Accession: | Q8NDG6,Q6ZU54, Q8N7T3, Q8N827, Q8N9V5, Q96AS9, A1A4S7 |
| UniProt Related Accession: | Q8NDG6 |
| Molecular Weight: | 134,466 Da |
| NCBI Full Name: | putative ATP-dependent RNA helicase TDRD9 |
| NCBI Synonym Full Names: | tudor domain containing 9 |
| NCBI Official Symbol: | TDRD9 |
| NCBI Official Synonym Symbols: | HIG-1; NET54; C14orf75 |
| NCBI Protein Information: | putative ATP-dependent RNA helicase TDRD9 |
| UniProt Protein Name: | Putative ATP-dependent RNA helicase TDRD9 |
| UniProt Synonym Protein Names: | Tudor domain-containing protein 9 |
| Protein Family: | Putative ATP-dependent RNA helicase |
| UniProt Gene Name: | TDRD9 |
| UniProt Entry Name: | TDRD9_HUMAN |
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