Developmental Biology
Anti-TDRD1 Antibody (CAB12882)
- SKU:
- CAB12882
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Description
| Antibody Name: | Anti-TDRD1 Antibody |
| Antibody SKU: | CAB12882 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-125 of human TDRD1 (NP_942090.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:1000 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse testis |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-125 of human TDRD1 (NP_942090.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | PFNF EKNE NKLP PHES LRSP GTLP NHPN FRLK SSEN GNKK NNFL LCEQ TKQY LASQ EDNS VSSN PNGI NGEV VGSK GDRK KLPA GNSV SPPS AESN SPPK E |
| Gene ID: | 56165 |
| Uniprot: | Q9BXT4 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 79kDa/119kDa/132kDa |
| Observed MW: | 132kDa |
| Synonyms: | TDRD1, CT41.1 |
| Background: | This gene is similar to a mouse gene that encodes a tudor domain protein. Alternatively spliced transcript variants have been described but their full length sequences have not been determined. |
| UniProt Protein Function: | TDRD1: Plays a central role during spermatogenesis by participating in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for the localization of Piwi proteins to the meiotic nuage. Involved in the piRNA metabolic process by ensuring the entry of correct transcripts into the normal piRNA pool and limiting the entry of cellular transcripts into the piRNA pathway. May act by allowing the recruitment of piRNA biogenesis or loading factors that ensure the correct entry of transcripts and piRNAs into Piwi proteins. Belongs to the TDRD1 family. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cancer Testis Antigen (CTA) Chromosomal Location of Human Ortholog: 10q25.3 Cellular Component: cytoplasm Biological Process: DNA methylation during gametogenesis; germ cell development; RNA-mediated gene silencing; spermatogenesis |
| NCBI Summary: | This gene is similar to a mouse gene that encodes a tudor domain protein. Alternatively spliced transcript variants have been described but their full length sequences have not been determined. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9BXT4 |
| NCBI GenInfo Identifier: | 206729901 |
| NCBI Gene ID: | 56165 |
| NCBI Accession: | Q9BXT4.2 |
| UniProt Secondary Accession: | Q9BXT4,Q4G0Y8, Q6P518, Q9H7B3, A6NEN3, A6NMN2, B3KVI4 B4E2L5, D3DRC2, |
| UniProt Related Accession: | Q9BXT4 |
| Molecular Weight: | 79,170 Da |
| NCBI Full Name: | Tudor domain-containing protein 1 |
| NCBI Synonym Full Names: | tudor domain containing 1 |
| NCBI Official Symbol: | TDRD1 |
| NCBI Official Synonym Symbols: | CT41.1 |
| NCBI Protein Information: | tudor domain-containing protein 1 |
| UniProt Protein Name: | Tudor domain-containing protein 1 |
| UniProt Synonym Protein Names: | Cancer/testis antigen 41.1; CT41.1 |
| Protein Family: | Tudor domain-containing protein |
| UniProt Gene Name: | TDRD1 |
| UniProt Entry Name: | TDRD1_HUMAN |
 | Western blot analysis of extracts of mouse testis, using TDRD1 Antibody (CAB12882) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
View AllClose
Related Products
Anti-RANBP3 Antibody (CAB0092)
OverviewProduct Name:RANBP3 Rabbit mAbProduct Code:CAB0092Size:20uL, 50uL, 100uLSynonyms:RANBP3, ran-binding protein 3
Anti-QK1 Antibody (CAB0193)
OverviewProduct Name:QK1 Rabbit mAbProduct Code:CAB0193Size:20uL, 50uL, 100uLSynonyms:QKI, Hqk, QK, QK1, QK3, hqkI, protein quaking
Anti-DEK Antibody (CAB0315)
OverviewProduct Name:DEK Rabbit mAbProduct Code:CAB0315Size:20uL, 50uL, 100uLSynonyms:D6S231EApplications:WB,
Anti-EXOSC7 Antibody (CAB0501)
OverviewProduct Name:EXOSC7 Rabbit mAbProduct Code:CAB0501Size:20uL, 50uL, 100uLSynonyms:EXOSC7, EAP1, RRP42, Rrp42p, hRrp42p, p8, exoso
Anti-Olig3 Antibody (CAB0600)
OverviewProduct Name:Olig3 Rabbit mAbProduct Code:CAB0600Size:20uL, 50uL, 100uLSynonyms:OLIG3, Bhlhb7, bHLHe20, oligodendrocyte transcri