Name: Anti-TBCC Antibody (CAB17537)
Brand: Cell Biology Antibodies 13
SKU: CAB17537
Availability: OutOfStock

Antibody Name:	Anti-TBCC Antibody
Antibody SKU:	CAB17537
Antibody Size:	20uL, 50uL, 100uL
Application:	WB IF
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-346 of human TBCC (NP_003183.1).

Application:	WB IF
Recommended Dilution:	WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:	Human, Mouse, Rat
Positive Samples:	HeLa, U-87MG, Mouse testis, Mouse brain, Mouse heart, Rat brain, Rat testis, Rat lung

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-346 of human TBCC (NP_003183.1).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	MESV SCSA AAVR TGDM ESQR DLSL VPER LQRR EQER QLEV ERRK QKRQ NQEV EKEN SHFF VATF ARER AAVE ELLE RAES VERL EEAA SRLQ GLQK LIND SVFF LAAY DLRQ GQEA LARL QAAL AERR RGLQ PKKR FAFK TRGK DAAS STKV DAAP GIPP AVES IQDS PLPK KAEG DLGP SWVC GFSN LESQ VLEK RASE LHQR DVLL TELS NCTV RLYG NPNT LRLT KAHS CKLL CGPV STSV FLED CSDC VLAV ACQQ LRIH STKD TRIF LQVT SRAI VEDC SGIQ FAPY TWSY PEID KDFE SSGL DRSK NNWN DVDD FNWL ARDM ASPN WSIL PEEE RNIQ WD
Gene ID:	6903
Uniprot:	Q15814
Cellular Location:
Calculated MW:	39kDa
Observed MW:	39kDa

Western blot - TBCC Polyclonal Antibody (CAB17537)

Synonyms:

CFC, TBCC

Background:

Cofactor C is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. [provided by RefSeq, Jul 2008]

UniProt Protein Function:	TBCC: Tubulin-folding protein; involved in the final step of the tubulin folding pathway. Belongs to the TBCC family.
UniProt Protein Details:	Chromosomal Location of Human Ortholog: 6p21.1 Cellular Component: cytoplasm; cytoskeleton; microtubule; photoreceptor connecting cilium Molecular Function:chaperone binding; GTPase activity Biological Process: post-chaperonin tubulin folding pathway; protein folding; tubulin folding
NCBI Summary:	Cofactor C is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. [provided by RefSeq, Jul 2008]
UniProt Code:	Q15814
NCBI GenInfo Identifier:	313104020
NCBI Gene ID:	6903
NCBI Accession:	Q15814.2
UniProt Secondary Accession:	Q15814,Q53Y43, Q5T787,
UniProt Related Accession:	Q15814
Molecular Weight:	39,248 Da
NCBI Full Name:	Tubulin-specific chaperone C
NCBI Synonym Full Names:	tubulin folding cofactor C
NCBI Official Symbol:	TBCC
NCBI Official Synonym Symbols:	CFC
NCBI Protein Information:	tubulin-specific chaperone C
UniProt Protein Name:	Tubulin-specific chaperone C
UniProt Synonym Protein Names:	Tubulin-folding cofactor C; CFC
Protein Family:	TBCC domain-containing protein
UniProt Gene Name:	TBCC
UniProt Entry Name:	TBCC_HUMAN