Anti-TAX1BP3 Antibody (CAB19793)
- SKU:
- CAB19793
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- TIP-1
- Synonyms:
- TIP1
- Research Area:
- Metabolism
Description
| Product Name: | TAX1BP3 Rabbit mAb |
| Product Code: | CAB19793 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | TIP-1, TIP1 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human TAX1BP3 |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | MCF7, NIH/3T3, Mouse lung, Mouse heart, Rat lung |
| Immunogen: | A synthesized peptide derived from human TAX1BP3 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 30851 |
| Uniprot: | O14907 |
| Calculated MW: | 14kDa |
| Observed MW: | 14KDa |
| UniProt Protein Function: | TAX1BP3: May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6. |
| UniProt Protein Details: | Protein type:Cell cycle regulation; Adaptor/scaffold Chromosomal Location of Human Ortholog: 17p13 Cellular Component: cytosol Molecular Function:protein binding; protein C-terminus binding Biological Process: negative regulation of Wnt receptor signaling pathway; Rho protein signal transduction |
| UniProt Code: | O14907 |
| NCBI GenInfo Identifier: | 74739481 |
| NCBI Gene ID: | 30851 |
| NCBI Accession: | O14907.2 |
| UniProt Secondary Accession: | O14907,Q7LCQ4, B2RD53, D3DTJ6, |
| UniProt Related Accession: | O14907 |
| Molecular Weight: | 13,735 Da |
| NCBI Full Name: | Tax1-binding protein 3 |
| NCBI Synonym Full Names: | Tax1 binding protein 3 |
| NCBI Official Symbol: | TAX1BP3 |
| NCBI Official Synonym Symbols: | TIP1; TIP-1 |
| NCBI Protein Information: | tax1-binding protein 3 |
| UniProt Protein Name: | Tax1-binding protein 3 |
| UniProt Synonym Protein Names: | Glutaminase-interacting protein 3; Tax interaction protein 1; TIP-1; Tax-interacting protein 1 |
| UniProt Gene Name: | TAX1BP3 |
| UniProt Entry Name: | TX1B3_HUMAN |
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